Protium 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Unimed unihealth pharmaceuticals ltd
Also available as
Protium 40 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. Inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus, persists longer than 24 hours.

Dosage & Administration

  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, may be increased to 40 mg daily
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
  • Duodenal ulcer associated with Helicobacter pylori: 40 mg twice daily in association with antimicrobial agents
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for those requiring long-term NSAID treatment
  • Zollinger-Ellison Syndrome: Initially 80 mg once daily adjusted according to response; elderly max. 40 mg daily; daily doses above 80 mg given in 2 divided doses
  • IV Injection for various conditions

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B. No adequate and well-controlled studies in pregnant women. Excretion in human milk. To be used during pregnancy only if clearly needed. Decision should be made whether to discontinue nursing or discontinue the drug, considering the benefit to the mother.

Precautions & Warnings

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12)
  • Increased risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans. Highly protein bound, not readily dialyzable. Symptomatic and supportive management; no specific therapy recommended

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

  • Directions for use of IV injection and IV infusion with details of reconstitution process and storage conditions

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

Molecular Formula: C16H15F2N3O4S, Chemical Structure image provided

Common Questions about Protium 20 mg Tablet

  • Description of the tablet and its indication
  • Dosage frequency as per prescription
  • Instructions for storage and disposal
  • Effects on older adults
  • Time taken to work
  • Safety aspects for pregnant or breastfeeding individuals
  • Missed dose instructions
  • Possible weight gain and side effects

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