Protium 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (4 x 7: ৳ 252.00)
Strip Price: ৳ 63.00

Medicine Details

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. It leads to the inhibition of both basal and stimulated gastric acid secretion.

Dosage & Administration

  • Oral
  • IV Injection

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B. No adequate and well-controlled studies in pregnant women. Drug should be used during pregnancy only if clearly needed. Pantoprazole excreted in human milk. Decision should be made whether to discontinue nursing or discontinue the drug.

Precautions & Warnings

  • Tablet should not be split, chewed, or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis-related disorders

Overdose Effects

No known symptoms of overdosage in humans. Highly protein bound, not readily dialyzable.

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

IV injection should be given slowly over a period. Reconstituted solution may be stored for a maximum 4 hours. IV infusion should be reconstituted and further diluted. The admixed solution may be stored at room temperature and must be used within 24 hours from the time of initial reconstitution.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure: Image provided

Common Questions about Protium 40 mg Tablet

  • Usage for Peptic ulcer diseases, GERD, Ulcer induced by NSAIDs, Eradication of Helicobacter pylori, Zollinger-Ellison Syndrome
  • Duration of use
  • Frequency of use
  • Usage with or without food
  • Storage and disposal instructions
  • Effects in older adults
  • Onset of action
  • Safety
  • Impact on weight
  • Side effects
  • Safety during pregnancy and breastfeeding
  • Missed dose instructions

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