Protium 40 mg (Tablet (Enteric Coated))
Medicine Details
Category | Details |
---|---|
Generic | Pantoprazole sodium |
Company | Unimed unihealth pharmaceuticals ltd |
Also available as |
Indications
- Peptic ulcer diseases
- Gastroesophageal reflux diseases
- Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
- Eradication of Helicobacter pylori (in combination with antibiotics)
- Zollinger-Ellison Syndrome
Pharmacology
Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. It leads to the inhibition of both basal and stimulated gastric acid secretion.
Dosage & Administration
- Oral
- IV Injection
Interaction
No significant drug interactions observed in clinical studies
Contraindications
Contraindicated in patients with known hypersensitivity to any of the components of the formulation
Side Effects
- Headache
- Diarrhea
- Abdominal pain
- Flatulence
- Rash
- Insomnia
- Hyperglycemia
Pregnancy & Lactation
US FDA Pregnancy Category B. No adequate and well-controlled studies in pregnant women. Drug should be used during pregnancy only if clearly needed. Pantoprazole excreted in human milk. Decision should be made whether to discontinue nursing or discontinue the drug.
Precautions & Warnings
- Tablet should not be split, chewed, or crushed
- Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis-related disorders
Overdose Effects
No known symptoms of overdosage in humans. Highly protein bound, not readily dialyzable.
Therapeutic Class
Proton Pump Inhibitor
Reconstitution
IV injection should be given slowly over a period. Reconstituted solution may be stored for a maximum 4 hours. IV infusion should be reconstituted and further diluted. The admixed solution may be stored at room temperature and must be used within 24 hours from the time of initial reconstitution.
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15F2N3O4S
- Chemical Structure: Image provided
Common Questions about Protium 40 mg Tablet
- Usage for Peptic ulcer diseases, GERD, Ulcer induced by NSAIDs, Eradication of Helicobacter pylori, Zollinger-Ellison Syndrome
- Duration of use
- Frequency of use
- Usage with or without food
- Storage and disposal instructions
- Effects in older adults
- Onset of action
- Safety
- Impact on weight
- Side effects
- Safety during pregnancy and breastfeeding
- Missed dose instructions
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