Protonil 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Renata limited
Also available as
Protonil 20 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

  • Proton pump inhibitor
  • H+/K+ ATPase enzyme system
  • Basal and stimulated gastric acid secretion inhibition
  • Long-lasting effect of more than 24 hours

Dosage & Administration

  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks
  • Duodenal ulcer associated with Helicobacter pylori: 40 mg twice daily in association with antimicrobial agents for one week
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily
  • Zollinger-Ellison Syndrome: Initially 80 mg once daily, adjusted according to response

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B, no adequate and well-controlled studies in pregnant women, excreted in human milk

Precautions & Warnings

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis related disorders

Overdose Effects

  • No known symptoms of overdosage in humans
  • Highly protein bound, not readily dialyzable

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

  • IV injection: should be given as a slow intravenous injection
  • IV infusion: should be given over a period of approximately 15 minutes
  • Reconstituted solution may be stored at room temperature for a maximum 4 hours prior to further dilution

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions about Protonil 40 mg Tablet

  • What is Protonil 40 mg Tablet?
  • How long do I need to use Protonil 40 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Protonil 40 mg Tablet?
  • Should I use Protonil 40 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Protonil 40 mg Tablet?
  • What are the effects of Protonil 40 mg Tablet on older adults?
  • How long does it take for Protonil 40 mg Tablet to work?
  • Is Protonil 40 mg Tablet safe?
  • Does Protonil 40 mg Tablet cause weight gain?
  • What are the side effects of Protonil 40 mg Tablet?
  • Can I take Protonil 40 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Protonil 40 mg Tablet?

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