Proton-P 20 mg (Tablet (Enteric Coated))
Medicine Details
| Category | Details |
|---|---|
| Generic | Pantoprazole sodium |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Peptic ulcer diseases
- Gastroesophageal reflux diseases
- Ulcer induced by NSAIDs
- Eradication of Helicobacter pylori
- Zollinger-Ellison Syndrome
Pharmacology
Suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell, leads to inhibition of both basal and stimulated gastric acid secretion
Dosage & Administration
- 40 mg daily in the morning for 4 weeks for benign gastric ulcer
- 20-40 mg daily in the morning for 4 weeks for GERD
- 40 mg daily in the morning for 2 weeks for duodenal ulcer
- 40 mg twice daily in association with antimicrobial agents for duodenal ulcer associated with Helicobacter pylori
- 20 mg daily for prophylaxis of NSAID-associated gastric or duodenal ulcer
- Initially 80 mg once daily for Zollinger-Ellison Syndrome
Interaction
No significant drug interactions observed in clinical studies
Contraindications
Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation
Side Effects
- Headache
- Diarrhea
- Abdominal pain
- Flatulence
- Rash
- Insomnia
- Hyperglycemia
Pregnancy & Lactation
US FDA Pregnancy Category B, not enough data in pregnant woman, excreted in human milk
Precautions & Warnings
- Tablet should not be split, chewed or crushed
- Long-term therapy may lead to malabsorption of Vitamin B12 or increase the risk of osteoporosis related disorders
Overdose Effects
No known symptoms of overdosage in humans, not readily dialyzable, no specific therapy recommended
Therapeutic Class
Proton Pump Inhibitor
Reconstitution
IV injection should be given slowly over a period, solution may be stored at room temperature for a maximum of 4 hours
Storage Conditions
Keep in a dry place, away from light and heat, out of the reach of children
Chemical Structure
- Molecular Formula: C16H15F2N3O4S
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg
Common Questions about Proton-P 20 mg Tablet
- What is Proton-P 20 mg Tablet?
- How long do I need to use Proton-P 20 mg Tablet before I see improvement in my condition?
- At what frequency do I need to use Proton-P 20 mg Tablet?
- Should I use Proton-P 20 mg Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Proton-P 20 mg Tablet?
- What are the effects of Proton-P 20 mg Tablet in older adults?
- How long does it take for Proton-P 20 mg Tablet to work?
- Is Proton-P 20 mg Tablet safe?
- Does Proton-P 20 mg Tablet cause weight gain?
- What are the side effects of Proton-P 20 mg Tablet?
- Can I take Proton-P 20 mg Tablet if I am pregnant or breastfeeding?
- What should I do if I miss a dose of Proton-P 20 mg Tablet?