Micogyl 500 mg/100 ml (IV Infusion)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Metronidazole
Company Globe pharmaceuticals ltd
Also available as
Micogyl 400 mg tablet Micogyl 200 mg suspension

ProductTitle

Micogyl 500 mg/100 ml Injection

ProductCategory

  • Medicine
  • Pharmaceuticals

Indications

  • Post-operative infections due to anaerobic bacteria
  • Septicaemia
  • Peritonitis
  • Brain abscess
  • Pelvic cellulitis
  • Urogenital trichomoniasis
  • Bacterial vaginosis
  • Amoebiasis
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers
  • Dental infections
  • Pseudomembranus colitis

Pharmacology

Member of the imidazole class of antibacterial drug

DosageAndAdministration

  • TabletAndSuspension:
    • Trichomoniasis - 200 mg tid or 400 mg bid for 7 days
    • Intestinal amoebiasis - 800 mg tid for 5 days
    • Extra-intestinal amoebiasis - 400-800 mg tid for 5-10 days
    • Giardiasis - 2 gm once daily for 3 days
    • Acute ulcerative gingivitis - 200 mg tid for 3 days
    • Bacterial Vaginosis - 400 mg bid for 7 days
    • Leg ulcers and pressure sores - 400 mg tid for 7 days
    • Anaerobic infections - 800 mg initially and then 400 mg tid for 7 days
    • Surgical prophylaxis - 400 mg tid started 24 hours before surgery for 1 day
  • VaginalGel: One applicator full intravaginally once or twice a day for 5 days
  • Suppository:
    • AnaerobicInfections: Adults: 1 g every 8 hours for 3 days, then 1 g every 12 hours. Children: 5-10 years - 500 mg every 8 hours for 3 days, then every 12 hours
    • SurgicalProphylaxis: Adults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high-risk procedures. Children: 5-10 years - 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high-risk procedures
  • IvInfusion:
    • AdultsAndChildrenOver12Years: Infuse 500 mg 8 hourly, with a maximum of 4 g in 24 hours. For surgical prophylaxis, administer shortly before surgery followed by 8-hourly doses for the next 24 hours
    • ChildrenUnder12Years: 7.5 mg/kg body weight/day every 8 hours

Interactions

  • Disulfiram
  • Alcohol
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

SideEffects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

PregnancyAndLactation

  • Category: US FDA Pregnancy Category B
  • Caution: Excreted in human milk. Caution during nursing.

PrecautionsAndWarnings

  • Longer administration recommended with hematological tests
  • Administer with caution to patients with hepatic encephalopathy
  • May darken urine

SpecialPopulations

  • HepaticImpairment: Administer with caution, reduce daily dosage
  • RenalImpairment: No reduction in dosage needed, caution in patients undergoing dialysis

OverdoseEffects

Symptomatic and supportive treatment for overdosages

TherapeuticClass

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

StorageConditions

Store below 30°C, protected from light, keep out of reach of children, do not use after expiry date

CommonQuestions

  • Micogyl500mgInjection:
    • Uses: Treatment and prevention from viral and parasitic infections, also controls bacterial infections
    • SideEffects:
      • Diarrhoea
      • Headache
      • Weakness
      • Painful urination

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