Flamyd 200 mg/5 ml (Oral Suspension)
Medicine Details
Category | Details |
---|---|
Generic | Metronidazole |
Company | Incepta pharmaceuticals ltd |
Also available as |
Product Title
Flamyd 200 mg/5 ml Suspension
Categories
- Antibiotics
- Antiprotozoal
- Amoebicides
- Anti-diarrhoeal
Description
Flamyd is indicated in the treatment of various diseases including post-operative infections, septicaemia, bacterial vaginosis, amoebiasis, giardiasis, ulcerative gingivitis, dental infections, and more. It is an antibiotic medication that works by preventing the growth of bacteria and parasites.
Dosage Forms
- Tablet
- Suspension
- Vaginal Gel
- Suppository
- IV Infusion
Dosage Instructions
- Trichomoniasis Adults & Children over 10 yrs:
- 200 mg tid for 7 days
- 400 mg bid for 7 days
- 800 mg in the morning and 1-2 gm at night for 2 days
- Trichomoniasis Children:
- Children 7-10 yrs: 100 mg tid
- Children 3-7 yrs: 100 mg bid
- Intestinal amoebiasis Adults & Children over 10 yrs: 800 mg tid for 5 days
- Intestinal amoebiasis Children:
- Children 7-10 yrs: 400 mg tid
- Children 3-7 yrs: 200 mg qid
- Extra-intestinal & Asymptomatic amoebiasis Adults & Children over 10 yrs: 400-800 mg tid for 5-10 days
- Extra-intestinal & Asymptomatic amoebiasis Children:
- Children 7-10 yrs: 200-400 mg tid
- Children 3-7 yrs: 100-200 mg qid
- Giardiasis Adults & Children over 10 yrs: 2 gm once daily for 3 days
- Giardiasis Children:
- Children 7-10 yrs: 1 gm once daily
- Children 3-7 yrs: 600-800 mg once daily
- Acute ulcerative gingivitis Adults & Children over 10 yrs: 200 mg tid for 3 days
- Acute ulcerative gingivitis Children:
- Children 7-10 yrs: 100 mg tid
- Children 3-7 yrs: 100 mg bid
- Acute dental infections Adults & Children over 10 yrs: 200 mg tid for 3-7 days
- Bacterial Vaginosis Adults & Children over 10 yrs:
- 400 mg bid for 7 days
- 2 gm as a single dose for 1 day
- Leg ulcers and pressure sores Adults & Children over 10 yrs: 400 mg tid for 7 days
- Anaerobic infections Adults & Children over 10 yrs: 800 mg initially and then 400 mg tid for 7 days
- Anaerobic infections Children: Children 1-10 yrs: 7.5 mg/kg tid
- Surgical prophylaxis Adults & Children over 10 yrs: 400 mg tid started 24 hours before surgery for 1 day
- Surgical prophylaxis Children: Children 1-10 yrs: 7.5 mg/kg tid
- Vaginal Gel: One applicator full once or twice a day for 5 days
- Suppository:
- Anaerobic Infections Adults: 1 g every 8 hours for 3 days, then 1 g every 12 hours
- Anaerobic Infections Children: 5-10 years: 500 mg every 8 hours for 3 days, then every 12 hours
- Surgical Prophylaxis Adults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures
- Surgical Prophylaxis Children: 5-10 years: 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures
- IV Infusion:
- Adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute
- Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute
Pharmacology
Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically. Studies have demonstrated that the reduced form of this drug interacts with DNA and gives bactericidal action of Metronidazole.
Indications
- Prevention of post-operative infections
- Septicaemia
- Bacteraemia
- Peritonitis
- Brain abscess
- Pelvic abscess
- Pelvic cellulitis
- Post-operative wound infections caused by anaerobes
- Urogenital trichomoniasis
- Bacterial vaginosis
- Amoebiasis
- Giardiasis
- Acute ulcerative gingivitis
- Anaerobically infected leg ulcers
- Pressure sores
- Acute dental infections
- Antibiotic-associated pseudomembranus colitis
Interaction
- Disulfiram
- Alcohol
- Lithium
- Cyclosporin
- Phenytoin or phenobarbital
- 5-Fluorouracil
- Busulfan
Contraindications
Metronidazole is contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives.
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
US FDA Pregnancy Category of Metronidazole is B. Caution should be exercised when Metronidazole is administered to a nursing woman.
Precautions & Warnings
- Regular hematological tests recommended for longer administrations
- Caution in patients with hepatic encephalopathy
- Warn patients that Flamyd may darken urine
Use in Special Populations
- Hepatic impairment: Flamyd should be administered with caution to patients with hepatic encephalopathy.
- Renal impairment: The elimination half-life of Flamyd remains unchanged in the presence of renal failure.
Overdose Effects
Symptoms of overdose include vomiting, ataxia, and slight disorientation. No specific antidote available.
Therapeutic Class
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
Store below 30°C. Keep protected from light. Keep medicines out of the reach of children. Do not use later than the date of expiry.
Commonly Asked Questions
- What is Flamyd 200 mg/5 ml Suspension?: An antibiotic medication preventing the growth of bacterias and parasites.
- What are the uses of Flamyd 200 mg/5 ml Suspension?: Treatment and prevention from viral and parasitic infections, and bacterial infections such as cold, cough, flu, vaginal infections, liver, skin, joints, brain, and respiratory tract infections.
- What are the side effects of Flamyd 200 mg/5 ml Suspension?: Diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, mouth ulcer.
- How long do I need to use Flamyd 200 mg/5 ml Suspension before I see improvement of my conditions?: 1 or 2 days before improvement is seen.
- What are the contraindications to Flamyd 200 mg/5 ml Suspension?: Hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
- Is Flamyd 200 mg/5 ml Suspension safe to use when pregnant?: Not recommended for use in pregnant women unless absolutely necessary.
- Will Flamyd 200 mg/5 ml Suspension be more effective if taken in more than the recommended dose?: No, higher dose increases chances of side effects.