Orbizol 400 mg (Tablet)

Unit Price: ৳ 1.00

Medicine Details

Category Details
Generic Metronidazole
Company Orbit pharmaceuticals ltd
Also available as

Product Title

  • Orbizol 400 mg Tablet

Therapeutic Class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections caused by anaerobes
  • Treatment of urogenital trichomoniasis
  • Bacterial vaginosis
  • Amoebiasis (intestinal, extra-intestinal disease)
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers and pressure sores
  • Acute dental infections due to anaerobic organisms
  • Antibiotic associated pseudomembranous colitis

Dosage & Administration

  • Recommended dosage for different indications and age groups

Mode of Action

  • Member of the imidazole class of antibacterial drug
  • Classified therapeutically as an antiprotozoal agent
  • The 5-nitro group is reduced by anaerobes metabolically
  • Interacts with DNA giving bactericidal action

Dosage Forms

  • Tablet
  • Suspension
  • Vaginal Gel
  • Suppository
  • IV Infusion

Interaction

  • Disulfiram
  • Alcohol
  • Oral anticoagulant therapy (warfarin type)
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side Effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy & Lactation

  • FDA Pregnancy Category B
  • Excreted in human milk
  • Administered to a nursing woman with caution

Precautions & Warnings

  • Regular hematological tests for prolonged use
  • Caution in patients with hepatic encephalopathy
  • May darken urine

Use in Special Populations

  • Hepatic impairment
  • Renal impairment

Overdose Effects

  • Symptomatic and supportive treatment
  • No specific antidote

Storage Conditions

  • Store below 30°C
  • Protected from light
  • Keep out of the reach of children
  • Do not use later than the date of expiry

Commonly Asked Questions

  • What is Orbizol 400 mg Tablet?
  • Uses of Orbizol 400 mg Tablet
  • Side effects of Orbizol 400 mg Tablet
  • Time to see improvement with Orbizol 400 mg Tablet
  • Contraindications to Orbizol 400 mg Tablet
  • Safety of Orbizol 400 mg Tablet during pregnancy
  • Effectiveness of higher than recommended dose
  • Quick Tips

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