Protozin 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Euro pharma ltd
Also available as
Protozin 20 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+-ATPase enzyme system at the surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus that persists longer than 24 hours.

Dosage & Administration

  • 40 mg daily in the morning for 4 weeks for benign gastric ulcer
  • 20-40 mg daily in the morning for 4 weeks for gastro-esophageal reflux disease
  • 40 mg daily in the morning for 2 weeks for duodenal ulcer
  • 40 mg twice daily in association with antimicrobial agents for duodenal ulcer associated with Helicobacter pylori
  • 20 mg daily for long-term NSAID treatment
  • 80 mg once daily for Zollinger-Ellison Syndrome
  • 40 mg once daily for 7-10 days for duodenal ulcer and gastric ulcer IV injection
  • 40 mg once daily for 7-10 days for gastroesophageal reflux disease IV injection
  • IV 80 mg followed by infusion for 72 hours for prevention of rebleeding in peptic ulcer
  • 80 mg IV every 12 h for 24 h for prophylaxis of acid aspiration
  • 80 mg IV every 12 hours for long-term management of Zollinger-Ellison Syndrome and other pathological hypersecretory conditions

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category of Pantoprazole is B. Limited studies in pregnant women. Excretion in human milk. Decision to use during pregnancy or nursing should consider benefit to the mother

Precautions & Warnings

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of Vitamin B12
  • May increase the risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans. Highly protein bound and not readily dialyzable.

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

  • IV injection should be given as a slow intravenous injection
  • IV infusion should be given as an intravenous infusion over a period of approximately 15 minutes
  • Reconstituted solution may be stored at room temperature for a maximum of 4 hours

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions

  • What is Protozin 40 mg Tablet?
  • How long do I need to use Protozin 40 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Protozin 40 mg Tablet?
  • Should I use Protozin 40 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Protozin 40 mg Tablet?
  • What are the effects of Protozin 40 mg Tablet on older adults?
  • How long does it take for Protozin 40 mg Tablet to work?
  • Is Protozin 40 mg Tablet safe?
  • Does Protozin 40 mg Tablet cause weight gain?
  • What are the side effects of Protozin 40 mg Tablet?
  • Can I take Protozin 40 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Protozin 40 mg Tablet?

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