Fungimin 2% w/w (Oral Gel)
20 gm tube: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Miconazole nitrate |
| Company | Kumudini pharma ltd |
| Also available as |
Title
Fungimin Oral Gel
Categories
- Medicine
- Oral Gel
- Antifungal
- Topical Cream
Description
Oral and topical antifungal treatment for candidiasis, dermatomycoses, and gram-positive bacterial superinfections
Indications
- Treatment of oral and gastrointestinal candidiasis
- Eradication of fungal colonization in the mouth and gastrointestinal tract
- Treatment of superinfections due to gram-positive bacteria
- Treatment of tinea pedis (athlete's foot), tinea corporis, tinea manuum, tinea cruris, candidial infections, tinea versicolor, skin infections, perianal infections, stomatitis angularis, balanoposthitis, otitis externa
Pharmacology
- Pharmacodynamics: Antifungal and antibacterial activity against common dermatophytes and yeasts, inhibition of ergosterol biosynthesis, disruption of fungal cell membrane
- Pharmacokinetics:
- Oral Bioavailability: Low (25-30%)
- Plasma Protein Binding: 88.2%
- Metabolism: Largely metabolized
- Elimination Half-life: 20-25 hours
Dosage
- Miconazole Oral Gel:
- Infants 4-24 months: 1.25 ml 4 times a day after meals
- Adults and children 2 years and older: 2.5 ml 4 times a day after meals
- Gastrointestinal tract candidosis for infants and adults: 20 mg per kg body weight per day in four divided doses, not to exceed 250 mg 4 times daily
- Miconazole Cream: Applied twice daily for tinea pedis, tinea cruris, tinea corporis, and cutaneous candidiasis; once daily for tinea versicolor
Administration
Direct application to affected area, keeping in contact for at least a week after symptoms disappear
Interaction
- Avoid concomitant use with Terfenadine, Astemizole, and Cisapride
- May delay metabolism of Phenytoin and Cyclosporine
Contraindications
Known hypersensitivity to miconazole
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Allergic reactions
Pregnancy & Lactation
Use with caution during pregnancy and nursing
Precautions & Warnings
Monitor anticoagulant and phenytoin levels, ensure gel does not obstruct the throat in infants and young children
Overdose Effects
Accidental overdosage may cause vomiting and diarrhea, treatment is symptomatic and supportive
Therapeutic Class
Aural Anti-fungal preparations
Storage Conditions
Keep in a dry place away from light and heat, out of the reach of children