Trazapin 30 mg (Tablet)

Unit Price: ৳ 15.00 (5 x 10: ৳ 750.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Mirtazapine
Company Albion laboratories limited
Also available as
Trazapin 15 mg tablet Trazapin 75 mg tablet

Indications

  • Treatment of major depressive disorder (MDD)

Pharmacology

  • Enhances central noradrenergic and serotonergic activity
  • Acts as an antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
  • Potent antagonist of 5-HT<sub>2</sub> and 5-HT<sub>3</sub> receptors
  • Potent antagonist of histamine (H<sub>1</sub>) receptors
  • Moderate peripheral &alpha;1-adrenergic antagonist
  • Moderate antagonist at muscarinic receptors
  • Rapid and well-absorbed after oral administration
  • Mean half-life of elimination is 20-40 hours
  • Displays linear pharmacokinetics within the recommended dose range
  • Extensively metabolized and eliminated via urine and feces

Dosage & Administration

  • Adult dose: 15 mg/day, administered in a single dose
  • Effective dose range: 15 to 45 mg/day
  • Use in children not recommended
  • Instructions for missed dose

Interaction

  • Clinically significant drug-drug interactions with certain drugs
  • Interactions with Monoamine Oxidase Inhibitors (MAOI) and other serotonergic drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to Mirtazapine or excipients
  • Contraindicated with Monoamine Oxidase Inhibitors (MAOI)

Side Effects

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Increased appetite
  • Weight gain

Pregnancy & Lactation

  • Pregnancy Category-C
  • Advice for patients who become pregnant or intend to become pregnant
  • Advice for breastfeeding patients

Precautions & Warnings

  • Alertness to emergence of certain behavioral changes
  • Risk of developing agranulocytosis
  • Impairment of judgment, thinking, and motor skills
  • Possibility of clinically significant ALT (SGPT) elevations

Therapeutic Class

  • Atypical anti-depressant drugs

Storage Conditions

  • Keep away from light and moisture
  • Store below 30&ordm; C
  • Keep out of the reach of children

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