Mirez 7.5 mg (Tablet)

Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00

Medicine Details

Indications

  • Treatment of major depressive disorder (MDD)

Pharmacology

  • Enhances central noradrenergic and serotonergic activity
  • Antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
  • Potent antagonist of 5- HT<sub>2</sub> and 5-HT<sub>3</sub> receptors
  • Antagonist of histamine (H<sub>1</sub>) receptors
  • Antagonist at muscarinic receptors
  • Metabolized and eliminated via the urine and faeces

Dosage & Administration

  • Recommended starting dose of 15 mg/day
  • Effective dose range of 15 to 45 mg/day
  • Children are not recommended to use Mirtazapine
  • Instructions for missed dose

Interaction

  • Clinically significant drug-drug interactions with MAOI & other serotonergic drugs
  • May interrupt the metabolism or activity of Carbamazepine, Phenytoin or Cimetidine
  • Avoid Alcohol & Diazepam while taking Mirez

Contraindications

  • Contraindicated in patients with known hypersensitivity
  • Concomitant use with MAO inhibitor is contraindicated

Side Effects

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Increased appetite
  • Weight gain

Pregnancy & Lactation

  • Pregnancy Category-C
  • Patients should notify physician if they become pregnant

Precautions & Warnings

  • Be alert to the emergence of adverse effects
  • Warned about the risk of developing agranulocytosis
  • May impair judgment, thinking, and motor skills
  • Clinically significant ALT (SGPT) elevations may occur

Therapeutic Class

  • Atypical anti-depressant drugs

Storage Conditions

  • Store below 30&ordm; C
  • Keep away from light and moisture
  • Keep all medicine out of the reach of children

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