Azapin 15 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Mirtazapine |
| Company | Labaid pharma ltd |
Title and Categories
- Azapin Tablets
- Atypical anti-depressant drugs
Indications
- Treatment of major depressive disorder (MDD)
Pharmacology
- Enhances central noradrenergic and serotonergic activity
- Antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
- Potent antagonist of 5-HT2 and 5-HT3 receptors
- Moderate peripheral α1-adrenergic antagonist
- Moderate antagonist at muscarinic receptors
- Potent antagonist of histamine (H1) receptors
- Extensively metabolized and eliminated via the urine and faeces
Dosage & Administration
- Recommended starting dose of 15 mg/day
- Effective dose range of 15 to 45 mg/day
- Elimination half-life of approximately 20 to 40 hours
- Dose changes should be made at intervals of less than 1 to 2 weeks
Interaction
- Clinically significant drug-drug interactions with MAO inhibitors & other serotonergic drugs
- May interrupt the metabolism or activity of Carbamazepine, Phenytoin, or Cimetidine
- Patient should avoid Alcohol & Diazepam
Contraindications
- Contraindicated in patients with hypersensitivity to Mirtazapine or excipients
- Concomitant use with a MAO inhibitor is contraindicated
Side Effects
- Dizziness
- Drowsiness
- Dry mouth
- Increased appetite
- Weight gain
Pregnancy & Lactation
- Pregnancy Category-C
- Patients should notify their physician if pregnant or intend to become pregnant during therapy
- Patients should notify their physician if breastfeeding
Precautions & Warnings
- Be alert to the emergence of various behavior changes
- Warned about the risk of developing agranulocytosis
- May impair judgment, thinking, and motor skills
- Clinically significant ALT (SGPT) elevations may occur
Storage Conditions
- Keep away from light and moisture
- Store below 30°C
- Keep all medicine out of the reach of children