Brocast 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Concord pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1).
Dosage & Administration
- 10 mg tablet once daily for adults and adolescents 15 years of age and older
- 5 mg tablet once daily for pediatric patients 6 to 14 years of age
- 4 mg tablet once daily for pediatric patients 2 to 5 years of age
- 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
Hepatic Insufficiency
No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency.
Renal Insufficiency
No dosage adjustment is recommended in patients with renal insufficiency.
Elderly use
The pharmacokinetic profile and the oral bioavailability of a single 10-mg oral dose of montelukast are similar in elderly and younger adults.
Interaction
Brocast has been administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma with no apparent increase in adverse reactions.
Contraindications
Montelukast is contraindicated in patients who are hypersensitive to any component of this product.
Side Effects
- Diarrhoea
- Fever
- Gastrointestinal discomfort
- Headache
- Nausea
- Vomiting
- Skin reactions
- Upper respiratory tract infection
- Akathisia
- Anxiety
- Arthralgia
- Asthenia
Pregnancy & Lactation
Montelukast crosses the placenta following oral dosing in rats and rabbits. Caution should be exercised when given to a nursing mother.
Precautions & Warnings
- Not for use in the reversal of bronchospasm in acute asthma attacks
- Patients should have appropriate rescue medication available
- Therapy can be continued during acute exacerbations of asthma
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Should not be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Brocast
Overdose Effects
The most frequently occurring adverse experiences were consistent with the safety profile of Brocast.
Therapeutic Class
Leukotriene receptor antagonists
Storage Conditions
Store in cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children.
Chemical Structure
- Molecular Formula: C35H36ClNO3S
- Chemical Structure ImageURL: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg
Common Questions
- What is Brocast 10 mg Tablet?: Brocast 10 mg Tablet is a selective and orally active leukotriene receptor antagonist.
- What is Brocast 10 mg Tablet used for?: Brocast 10 mg Tablet is commonly used to treat asthma or allergic rhinitis.
- How soon can the effect of Brocast 10 mg Tablet be observed?: The effect of Brocast 10 mg Tablet can be observed after 1-3 hours of administration.
- How long does the effect of Brocast 10 mg Tablet last?: The effect of Brocast 10 mg Tablet lasts for an average duration of 24 hours.
- Should I use Brocast 10 mg Tablet empty stomach?: Brocast 10 mg Tablet may be taken with or without food as prescribed by your doctor.
- What if I miss a dose of Brocast 10 mg Tablet?: If you miss a dose, you may take it as soon as possible. But if it is almost time for your next dose, just skip that dose. Do not double up on doses.