Rabe 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (7 x 20: ৳ 980.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rabeprazole sodium |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Treatment of active benign gastric ulcer
- Treatment of symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
- Long-term management of gastro-esophageal reflux disease (GERD Maintenance)
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
- Treatment of Zollinger-Ellison Syndrome
- Combination therapy for the eradication of Helicobacter pylori in patients with peptic ulcer disease
Pharmacology
- Suppresses gastric acid secretion
- Inhibits the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell
- Characterized as a gastric proton-pump inhibitor
Dosage
- Recommended dose for active duodenal ulcer and active benign gastric ulcer: 20 mg once daily in the morning
- Recommended dose for erosive or ulcerative gastro-esophageal reflux disease (GERD): 20 mg once daily for 4-8 weeks
- Recommended dose for gastro-esophageal reflux disease long-term management: 20 mg or 10 mg once daily
- Recommended dose for treatment of symptomatic GERD: 10 mg once daily
- Recommended dose for treatment of Zollinger-Ellison Syndrome: 60 mg once daily, may titrate upwards to 120 mg/day
- Recommended dose for eradication of H. pylori: Rabeprazole sodium 20 mg twice daily
Administration
- Tablets should be taken in the morning before eating
- Tablets should not be chewed or crushed, but should be swallowed whole
Interaction
- Potential interaction with compounds whose absorption is pH dependent
- Potential interaction with ketoconazole or itraconazole leading to decreased antifungal plasma levels
Contraindications
- Hypersensitivity to the active substance or any of the excipients
- Contra-indicated in pregnancy and during breastfeeding
Side Effects
- Headache
- Diarrhoea
- Abdominal pain
- Vomiting
- Constipation
- Dry mouth
- Increased or decreased appetite
- Muscle pain
- Drowsiness
- Dizziness
Pregnancy & Lactation
- US FDA pregnancy category 'C'
- Excretion in human milk
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric or oesophageal malignancy
- Regular surveillance for long-term treatment patients
- Risk of hip, wrist, and spine fracture with long-term high-dose use
- Risk of cross-hypersensitivity reactions with other proton pump inhibitor or substituted benzimidazoles
- Caution in patients with mild to moderate hepatic impairment
- Hypomagnesaemia reported in patients treated for at least three months
- Reduction in vitamin B12 absorption
Use in Special Populations
- No dosage adjustment necessary for patients with renal or hepatic impairment
- Not recommended for use in children
Overdose Effects
- Effects are generally minimal and reversible without further medical intervention
- No specific antidote known
- Not dialysable due to extensive protein binding
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H21N3O3S
Common Questions
- What is Rabe 20 mg Tablet?
- What is Rabe 20 mg Tablet used for?
- What are the side effects of Rabe 20 mg Tablet?
- How should I take Rabe 20 mg Tablet?
- Can I take Rabe 20 mg Tablet while pregnant or breastfeeding?
- What should I do if I overdose on Rabe 20 mg Tablet?
- How long should I take Rabe 20 mg Tablet?
- Is there anything else I should know about Rabe 20 mg Tablet?
- Does Rabe 20 mg Tablet cause bone problems?
- Can I take Rabe 20 mg Tablet with vitamin D?