Medikast 4 mg (Chewable Tablet)

Unit Price: ৳ 6.00 (20's pack: ৳ 120.00)

Medicine Details

Category Details
Generic Montelukast sodium
Company Leon pharmaceuticals ltd
Also available as
Medikast 5 mg chewable tablet Medikast 10 mg tablet

Title

  • Medikast 4 mg Chewable Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmacology

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Montelukast is a selective and orally active leukotriene receptor antagonist
  • Inhibition of the cysteinyl leukotriene receptor (CysLT1)
  • Inhibition of cysteinyl leukotrienes (LTC4, LTD4, LTE4) released from mast cells and eosinophils
  • Correlation with the pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Adult dosage: 10 mg tablet once daily
  • Pediatric dosage: 5 mg tablet for 6-14 years, 4 mg tablet for 2-5 years, 4 mg oral granules for 6 months-5 years
  • No dosage adjustment in mild-to-moderate hepatic insufficiency or renal insufficiency
  • Similar pharmacokinetic profile in elderly

Interaction

  • No clinically important effects on the pharmacokinetics of theophylline, prednisone, oral contraceptives, terfenadine, digoxin, and warfarin
  • Used concomitantly with thyroid hormones, sedative hypnotics, NSAIDs, benzodiazepines, and decongestants
  • Phenobarbital decreased AUC of Montelukast by approximately 40%

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, headache, nausea, skin reactions
  • Uncommon: Anxiety, depression, dizziness, dry mouth, irritability, muscle complaints
  • Rare: Angioedema, disorientation, hallucination, hepatic disorders, memory loss, pulmonary eosinophilia, suicidal tendencies

Pregnancy & Lactation

  • Crosses the placenta in rats and rabbits
  • Use during pregnancy only if clearly needed
  • Caution when given to a nursing mother

Precautions & Warnings

  • Not for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Therapy can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not for monotherapy in the treatment of exercise-induced bronchospasm
  • Use with caution in aspirin-sensitive patients

Overdose Effects

  • No adverse experiences in the majority of overdose reports
  • Usual supportive measures recommended in case of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Commonly Asked Questions

  • What is Medikast 4 mg Chew. Tablet?
  • What is Medikast 4 mg Chew. Tablet used for?
  • How soon can the effect be observed?
  • How long does the effect last?
  • Should it be taken empty stomach?
  • What if a dose is missed?
  • Are there any pregnancy warnings?
  • General Instructions

Additional Information

  • Medikast helps keep airways open and facilitates easy breathing by blocking leukotrienes
  • Can be taken with or without food as prescribed by a doctor
  • Averages 24-hour duration of effect

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