Recast 4 mg (Chewable Tablet)

Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Category Details
Generic Montelukast sodium
Company Monicopharma ltd
Also available as
Recast 10 mg tablet Recast 5 mg chewable tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Montelukast is a selective and orally active leukotriene receptor antagonist
  • Inhibition of the cysteinyl leukotriene receptor (CysLT1)

Dosage & Administration

  • For adults and adolescents (15 years and older): 10 mg tablet once daily
  • For pediatric patients (6 to 14 years of age): 5 mg tablet once daily
  • For pediatric patients (2 to 5 years of age): 4 mg tablet once daily
  • For pediatric patients (6 months to 5 years of age): 4 mg oral granules once daily
  • Use in pediatric patients: established safety and efficacy in adequate and well-controlled studies
  • Hepatic Insufficiency: no dosage adjustment required for mild-to-moderate hepatic insufficiency
  • Renal Insufficiency: no dosage adjustment recommended for patients with renal insufficiency
  • Elderly use: similar pharmacokinetic profile and oral bioavailability as younger adults

Interaction

  • No clinically important effects on the pharmacokinetics of various drugs
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital induced hepatic metabolism, decreasing the AUC of Recast by approximately 40%

Contraindications

Hypersensitivity to any component of the product

Side Effects

  • Common:
    • Diarrhoea
    • Fever
    • Gastrointestinal discomfort
    • Headache
    • Nausea
    • Vomiting
    • Skin reactions
    • Upper respiratory tract infection
  • Uncommon:
    • Akathisia
    • Anxiety
    • Arthralgia
    • Asthenia
    • Abnormal behavior
  • Rare:
    • Angioedema
    • Concentration impaired
    • Disorientation
    • Eosinophilic granulomatosis with polyangiitis
    • Erythema nodosum

Pregnancy & Lactation

  • Montelukast crosses the placenta in rats and rabbits
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Therapy can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Caution advised for patients with known aspirin sensitivity

Overdose Effects

  • No adverse experiences in the majority of overdosage reports
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

Leukotriene receptor antagonists

Storage Conditions

Store in cool and dry place below 30°C, protect from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg

Common Questions about Recast 4 mg Chewable Tablet

  • What is Recast 4 mg Chew. Tablet?: A selective and orally active leukotriene receptor antagonist
  • What is Recast 4 mg Chew. Tablet used for?: Treatment of asthma or allergic rhinitis
  • How soon can the effect be observed?: 1-3 hours after administration
  • Duration of effect: Average duration of 24 hours
  • Usage with or without food: As prescribed by doctor
  • Pregnancy warnings: Use should be avoided unless clearly needed

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