Airway 10 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | One pharma ltd |
| Also available as |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Selective and orally active leukotriene receptor antagonist
- Inhibition of cysteinyl leukotriene receptor (CysLT1)
- Correlation with the pathophysiology of asthma & allergic rhinitis
- Contribution to signs and symptoms of asthma
Dosage & Administration
- Dosage for adults and adolescents 15 years of age and older: Montelukast 10 mg tablet once daily
- Dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
- Dosage for pediatric patients 2 to 5 years of age: Montelukast 4 mg tablet once daily
- Dosage for pediatric patients 6 months to 5 years of age: Montelukast 4 mg oral granules once daily
- Administration directly in the mouth or mixed with a spoonful of cold water or soft food at room temperature
- No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
- No dosage adjustment recommended in patients with renal insufficiency
- Similar pharmacokinetic profile and oral bioavailability in elderly and younger adults
- Slightly longer plasma half-life in the elderly
Interaction
- No apparent increase in adverse reactions when administered with other therapies for asthma
- No clinically important effects on the pharmacokinetics of specific drugs
- Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
- Phenobarbital decreased the AUC of Airway by approximately 40%
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
- Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy & Lactation
- Crosses the placenta
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Patients should have appropriate rescue medication available
- Therapy with Airway can be continued during acute exacerbations of asthma
- Dose of inhaled corticosteroid should be reduced gradually under medical supervision
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Should not be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Airway
Overdose Effects
- No adverse experiences in the majority of overdosage reports
- Adverse experiences consistent with the safety profile of Airway
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C35H36ClNO3S
Common Questions about Airway 10 mg Tablet
- Used to treat asthma or allergic rhinitis
- Helps keep airways open and improve breathing by blocking leukotrienes
- Effect can be observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours