Lukas 10 mg (Tablet)
Unit Price: ৳ 14.00 (30's pack: ৳ 420.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Premier pharmaceuticals ltd |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Selective and orally active leukotriene receptor antagonist
- Inhibition of the cysteinyl leukotriene receptor (CysLT1)
- Correlation with the pathophysiology of asthma & allergic rhinitis
Dosage administration
- Adult dosage: 10 mg tablet once daily
- Pediatric dosage: 5 mg tablet once daily for 6 to 14 years of age
- Pediatric dosage: 4 mg tablet once daily for 2 to 5 years of age
- Pediatric dosage: 4 mg oral granules once daily for 6 months to 5 years of age
- No dosage adjustment in hepatic or renal insufficiency
- Similar pharmacokinetic profile in elderly
Interaction
- No increase in adverse reactions when administered with other therapies
- No clinically important effects on the pharmacokinetics of specified drugs
- Used concomitantly with a wide range of commonly prescribed drugs without clinical adverse interactions
- Phenobarbital induces hepatic metabolism and decreases AUC of Lukas
- Appropriate clinical monitoring when co-administered with potent cytochrome P450 enzyme inducers
Contraindications
- Hypersensitivity to any component of this product
Side effects
- Common: Diarrhea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, hemorrhage, irritability, malaise, muscle complaints, edema, seizure, abnormal sensation, sleep disorders
- Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy lactation
- Crosses the placenta in animals
- Use during pregnancy only if clearly needed
- Caution in nursing mothers
Precautions warnings
- Not indicated for the reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Can be continued during acute exacerbations of asthma
- Not to be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Caution in patients with known aspirin sensitivity
- No truncation of bronchoconstrictor response to aspirin and other non-steroidal anti-inflammatory drugs in aspirin-sensitive asthmatic patients
Overdose effects
- Most commonly reported adverse experiences consistent with the safety profile of Lukas
- Usual supportive measures recommended in the event of overdose
Therapeutic class
- Leukotriene receptor antagonists
Storage conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical structure
- Molecular formula: C35H36ClNO3S
- Chemical structure image: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg
Common questions
- What is Lukas 10 mg Tablet?: A selective and orally active leukotriene receptor antagonist
- What is Lukas 10 mg Tablet used for?: Treatment of asthma or allergic rhinitis
- How soon can the effect be observed?: Within 1-3 hours of administration
- How long does the effect last?: An average duration of 24 hours
- Should it be taken empty stomach?: May be taken with or without food as prescribed
- Are there any pregnancy warnings?: Use should be avoided unless clearly needed
- General Instructions:
- Take exactly as prescribed by your doctor
- Do not change dose without doctor's advice
- Not a fast-acting rescue medicine for asthma attacks
- Avoid situations or activities that may trigger an asthma attack
- Caution if pregnant or breastfeeding