Antaluk 10 mg (Tablet)
Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | United pharmaceuticals ltd |
Title and Category
- Antaluk 10 mg Tablet
- Medicine
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1)
- Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma & allergic rhinitis
Dosage & Administration
- Adult dosage: Montelukast 10 mg tablet once daily
- Pediatric dosage: 6 to 14 years - 5 mg tablet once daily, 2 to 5 years - 4 mg tablet once daily, 6 months to 5 years - 4 mg oral granules once daily
Hepatic and Renal Insufficiency
- No dosage adjustment required
Elderly Use
- Pharmacokinetic profile and oral bioavailability is similar to younger adults
- Slightly longer plasma half-life in the elderly
Drug Interactions
- No clinically important effects on the pharmacokinetics of multiple drugs
- Concomitant use with a wide range of commonly prescribed drugs without evidence of adverse interactions
- Phenobarbital decreased the AUC of Antaluk by approximately 40%
Contraindications
- Hypersensitivity to any component of the product
Common Side Effects
- Diarrhoea
- Fever
- Gastrointestinal discomfort
- Headache
- Nausea
- Vomiting
- Skin reactions
- Upper respiratory tract infection
Uncommon Side Effects
- Akathisia
- Anxiety
- Arthralgia
- Asthenia
- Abnormal behavior
- Depression
- Dizziness
- Drowsiness
- Dry mouth
Rare Side Effects
- Angioedema
- Concentration impaired
- Disorientation
- Eosinophilic granulomatosis with polyangiitis
- Erythema nodosum
- Hallucination
- Hepatic disorders
- Memory loss
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
Overdose Effects
- No adverse experiences in the majority of reports
- Usual supportive measures recommended in the event of overdose
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C35H36ClNO3S
Commonly Asked Questions
- Antaluk 10 mg Tablet is a selective and orally active leukotriene receptor antagonist
- Used for the treatment of asthma or allergic rhinitis
- Effect can be observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours
- May be taken with or without food
- Use during pregnancy should be avoided unless clearly needed
- General instructions for usage
Usability Features
- Block leukotrienes to keep airways open
- Help in easy breathing
- Not a fast-acting rescue medicine for asthma attacks
Dosage for Different Age Groups
- Adult: 10 mg tablet once daily
- 6-14 years: 5 mg tablet once daily
- 2-5 years: 4 mg tablet once daily
- 6 months-5 years: 4 mg oral granules once daily
- No dosage adjustment for hepatic and renal insufficiency
Interaction with Other Therapies
- No apparent increase in adverse reactions
- Clinical dose did not have clinically important effects on the pharmacokinetics of multiple drugs
- Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
Side Effects Severity
- Common
- Uncommon
- Rare
Storage Instructions
- Keep in a cool and dry place below 30°C
- Protect from light and moisture
- Keep out of reach of children
Pregnancy and Lactation Caution
- Use during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Pharmacological Action
- Selective and orally active leukotriene receptor antagonist
- Inhibits the cysteinyl leukotriene receptor (CysLT1)
- Correlated with the pathophysiology of asthma & allergic rhinitis
Chemical Composition
- Molecular Formula: C35H36ClNO3S
Usability Recommendations
- Continue therapy during acute exacerbations of asthma
- Do not abruptly substitute for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
Interaction with Other Drugs
- No clinically important effects on the pharmacokinetics of multiple drugs
- Concomitant use with a wide range of commonly prescribed drugs without evidence of adverse interactions
- Phenobarbital decreased the AUC of Antaluk by approximately 40%
Side Effects Management
- Common and uncommon side effects may include gastrointestinal discomfort, headache, and nausea
- In the event of overdose, recommend the usual supportive measures
Usage Precautions
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Avoid abrupt substitution for inhaled or oral corticosteroids
Elderly Use Recommendations
- No dosage adjustment required
- Similar pharmacokinetic profile and oral bioavailability to younger adults