Monalast 10 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Ziska pharmaceuticals ltd
Also available as
Monalast 5 mg tablet Monalast odt 4 mg tablet

Title

  • Monalast 10 mg Tablet

Categories

  • Medicine
  • Healthcare
  • Treatment

Description

  • Monalast is indicated for prophylaxis and chronic treatment of asthma, acute prevention of Exercise-Induced Bronchoconstriction (EIB), and relief of symptoms of Allergic Rhinitis (AR) including seasonal & perennial allergic rhinitis.

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Selective and orally active leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Inhibits cysteinyl leukotrienes (LTC4, LTD4, LTE4) released from cells correlated with pathophysiology of asthma & allergic rhinitis

Dosage and administration

  • Dosage for adults and adolescents 15 years and older: 10 mg tablet once daily
  • Dosage for pediatric patients 6 to 14 years of age: 5 mg tablet once daily
  • Dosage for pediatric patients 2 to 5 years of age: 4 mg tablet once daily
  • Dosage for pediatric patients 6 months to 5 years of age: 4 mg oral granules once daily
  • No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency
  • No dosage adjustment is recommended in patients with renal insufficiency
  • No dosage adjustment is required in the elderly
  • Safety and efficacy established in pediatric patients with asthma 6 months to 14 years of age

Interaction

  • No clinically important effects on the pharmacokinetics of several drugs including theophylline, prednisone, oral contraceptives, terfenadine, digoxin, and warfarin
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital decreased the AUC of Monalast by approximately 40%
  • Clinical monitoring recommended when potent cytochrome P450 enzyme inducers are co-administered with Monalast

Contraindications

  • Montelukast is contraindicated in patients who are hypersensitive to any component of this product

Side effects

  • Common side effects include diarrhea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon side effects include anxiety, depression, dizziness, dry mouth, muscle complaints, seizure, sleep disorders
  • Rare side effects include angioedema, hallucination, hepatic disorders, memory loss, suicidal tendencies, tremor

Pregnancy and lactation

  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions and warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Patients advised to have appropriate rescue medication available
  • Therapy can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Monalast

Overdose effects

  • Adverse experiences consistent with the safety profile of Monalast including abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity
  • Usual supportive measures recommended in the event of overdose

Therapeutic class

  • Leukotriene receptor antagonists

Storage conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure: (image url)

Commonly asked questions

  • What is Monalast 10 mg Tablet?
  • What is Monalast 10 mg Tablet used for?
  • How soon can the effect be observed?
  • How long does the effect last?
  • Should it be taken empty stomach?
  • What if a dose is missed?
  • Are there any pregnancy warnings?
  • General instructions

Dimension

  • 10 mg tablet

Color options

  • Not applicable

Functions

  • Selectively blocks leukotrienes to treat asthma and allergic rhinitis

Materials

  • Not applicable

Technical specifications

  • Molecular Formula: C35H36ClNO3S

Design elements

  • Chemical structure image

Usability features

  • Suitable for adults, adolescents, and pediatric patients

Other features

  • No required dosage adjustment for hepatic insufficiency
  • No required dosage adjustment for renal insufficiency
  • Similar safety and efficacy in pediatric patients and elderly adults

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