Monalast 5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Ziska pharmaceuticals ltd
Also available as
Monalast 10 mg tablet Monalast odt 4 mg tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1).

Dosage & Administration

  • Adults and Adolescents: Montelukast 10 mg tablet once daily
  • Pediatric Patients:
    • 6 to 14 years: Montelukast 5 mg tablet once daily
    • 2 to 5 years: Montelukast 4 mg tablet once daily
    • 6 months to 5 years: Montelukast 4 mg oral granules once daily
  • Hepatic Insufficiency: No dosage adjustment required
  • Renal Insufficiency: No dosage adjustment recommended
  • Elderly Use: Similar pharmacokinetic profile to younger adults, slightly longer plasma half-life

Interaction

No clinically important effects on the pharmacokinetics of specific drugs observed. Caution with cytochrome P450 enzyme inducers.

Contraindications

Hypersensitivity to any component of this product

Side Effects

  • Common:
    • Diarrhoea
    • Fever
    • Gastrointestinal discomfort
    • Headache
    • Nausea
    • Vomiting
    • Skin reactions
    • Upper respiratory tract infection
  • Uncommon:
    • Akathisia
    • Anxiety
    • Arthralgia
    • Asthenia
    • Abnormal behavior
    • Depression
    • Dizziness
    • Drowsiness
    • Dry mouth
    • Haemorrhage
    • Irritability
    • Malaise
    • Muscle complaints
    • Oedema
    • Seizure
    • Abnormal sensation
    • Sleep disorders
  • Rare:
    • Angioedema
    • Concentration impaired
    • Disorientation
    • Eosinophilic granulomatosis with polyangiitis
    • Erythema nodosum
    • Hallucination
    • Hepatic disorders
    • Memory loss
    • Palpitations
    • Pulmonary eosinophilia
    • Suicidal tendencies
    • Tremor

Pregnancy & Lactation

Use during pregnancy only if clearly needed. Caution during nursing.

Precautions & Warnings

  • Not Indicated for: Reversal of bronchospasm in acute asthma attacks
  • Appropriate Rescue Medication: Should be available
  • Monotherapy: Should not be used for the treatment of exercise induced bronchospasm
  • Aspirin Sensitivity: Continue avoidance of aspirin or non-steroidal anti-inflammatory agents
  • Exacerbations of Asthma: Therapy can be continued

Overdose Effects

No adverse experiences in majority of reports. Supportive measures should be employed in the event of overdose.

Therapeutic Class

Leukotriene receptor antagonists

Storage Conditions

Store in cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children.

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg

Common Questions

  • What is it: Selective and orally active leukotriene receptor antagonist
  • Used for: To treat asthma or allergic rhinitis
  • Effect Onset: 1-3 hours after administration
  • Effect Duration: Approximately 24 hours
  • Administration: May be taken with or without food as prescribed
  • Missed Dose: Take as soon as possible, but do not double up on doses
  • Pregnancy Warnings: Avoid use unless clearly needed

Related Brands