Rabizol 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 14: ৳ 980.00)

Strip Price: ৳ 98.00

Medicine Details

Category	Details
Generic	Rabeprazole sodium
Company	Acme laboratories ltd

Indications

Active duodenal ulcer
Active benign gastric ulcer
Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
Zollinger-Ellison Syndrome
In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Suppresses gastric acid secretion
Inhibits the gastric H+/K+-ATPase
Characterized as a gastric proton-pump inhibitor

Dosage

Active Duodenal Ulcer and Active Benign Gastric Ulcer: 20 mg once daily in the morning
Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD): 20 mg once daily for 4-8 weeks
Gastro-Esophageal Reflux Disease Long-term Management (GERD Maintenance): 20 mg or 10 mg once daily
Symptomatic treatment of moderate to very severe Gastro-Esophageal Reflux Disease (symptomatic GERD): 10 mg once daily
Treatment of GERD in pediatric patients 1 to 11 years of age (Less than 15 kg): 5 mg once daily for 12 weeks
Treatment of GERD in pediatric patients 1 to 11 years of age (15 kg or more): 10 mg once daily for 12 weeks
Zollinger-Ellison Syndrome: 60-120 mg once daily

Administration

To be taken in the morning, before eating; should not be chewed or crushed, but should be swallowed whole

Interaction

Potential interaction with compounds whose absorption is pH dependent
Co-administration with ketoconazole or itraconazole may result in decreased antifungal plasma levels
No interaction with liquid antacids observed
Not recommended to be co-administered with atazanavir

Contraindications

Hypersensitivity to the active substance or to any of the excipients
Contra-indicated in pregnancy and during breastfeeding

Side Effects

Headache
Diarrhoea
Abdominal pain
Vomiting
Constipation
Dry mouth
Increased or decreased appetite
Muscle pain
Drowsiness
Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'; likely to be excreted in human milk

Precautions & Warnings

Symptomatic response does not preclude the presence of gastric or oesophageal malignancy
Modestly increase the risk of hip, wrist and spine fracture, predominantly in the elderly or in presence of other recognised risk factors
Risk of cross-hypersensitivity reactions with other proton pump inhibitor or substituted benzimidazoles
Potential blood dyscrasias and hepatic enzyme abnormalities
Co-administration with atazanavir not recommended
Possible increase in the risk of gastrointestinal infections such as Salmonella, Campylobacter and Clostridium difficile

Use in Special Populations

No dosage adjustment for patients with renal or hepatic impairment
Not recommended for use in children due to a lack of data on safety and efficacy

Overdose Effects

Maximum established exposure has not exceeded 60 mg twice daily or 160 mg once daily; effects are generally minimal, reversible without further medical intervention

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C, away from light & moisture, out of the reach of children

Chemical Structure

Molecular Formula: C18H21N3O3S
Chemical Structure Image: https://medex.com.bd/storage/res/g-res-942-rabeprazole-sodium-chemical-structure-atwg0Q4PlndQZhOY9GHX.svg

Common Questions about Rabizol 20 mg Tablet

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