Rabonac 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Sharif pharmaceuticals ltd

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • Eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase

Dosage

20 mg once daily in the morning for various conditions, including duodenal ulcer, gastric ulcer, GERD, Zollinger-Ellison Syndrome, and pediatric treatment

Administration

Tablets should be taken in the morning, before eating and should not be chewed or crushed

Interaction

  • Potential interaction with compound absorption
  • Co-administration with ketoconazole or itraconazole may decrease antifungal plasma levels
  • No interaction with liquid antacids
  • Not recommended with atazanavir due to its pH-dependent absorption

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C', no adequate and well-controlled studies in pregnant women

Precautions & Warnings

  • Malignancy should be excluded prior to commencing treatment
  • Regular surveillance for long-term treatment
  • Modestly increased risk of hip, wrist, and spine fractures in high doses and long durations
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors
  • Hepatic enzyme abnormalities seen in clinical trials
  • No dosage adjustment for renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

Effects are generally minimal and reversible without further medical intervention, no specific antidote known

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C temperature, away from light & moisture, keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H21N3O3S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-942-rabeprazole-sodium-chemical-structure-atwg0Q4PlndQZhOY9GHX.svg

Common Questions

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