Napryn 125 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- rheumatoid arthritis
- osteoarthritis
- ankylosing spondylitis
- juvenile arthritis
- tendonitis
- bursitis
- acute gout
- dysmenorrhea & pain management
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreased prostaglandin synthesis
- Antipyretic, analgesic, and anti-inflammatory properties
Dosage & Administration
- Taken with water after meals
- Oral tablet and suspension options
- Dosage varies for different indications and age groups
Interaction
- Diminishes antihypertensive effect of ACE inhibitors
- Delays absorption with antacids & sucralfate
- Enhances toxicity of methotrexate
- Increases risk of GI bleeding with warfarin and SSRIs
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System: Headache, vertigo, drowsiness
- Dermatological: Pruritus (itching), purpura
- Cardiovascular: Edema, palpitation
- Others: Visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effects on fetus
- Delay in parturition
- Premature closure of ductus arteriosus and severe pulmonary hypertension in infants
- Excretion in breast milk
- Balancing benefits to mother against risks to fetus
- Small amounts in breast milk, cautious balancing of benefits and risks
Precautions & Warnings
- Renal effects: Reports of renal papillary necrosis and abnormal renal pathology
- Acute interstitial nephritis, hematuria, proteinuria, nephrotic syndrome
- Eliminated primarily by the kidneys, caution in impaired renal function
- Monitoring of serum creatinine and/or creatinine clearance recommended
- Hepatic effects: Moderate to severe jaundice reported
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children