Aktivex 500 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Naproxen sodium
Company Osl pharma limited
Also available as

Indications

  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • juvenile arthritis
  • tendonitis
  • bursitis
  • acute gout
  • primary dysmenorrhea & pain

Pharmacology

  • COX-1 and COX-2 enzyme blockage
  • decreased prostaglandin synthesis
  • antipyretic properties
  • analgesic properties
  • anti-inflammatory properties
  • gastrointestinal upset
  • renal toxicities

Dosage & Administration

  • Naproxen oral preparations
  • enteric coated tablet for adults
  • enteric coated tablet for children
  • suspension for children
  • naproxen gel
  • dosage for rheumatoid arthritis/osteoarthritis/ankylosing spondylitis
  • dosage for acute gout
  • dosage for dysmenorrhoea
  • dosage for analgesia and acute musculoskeletal disorders
  • dosage for juvenile rheumatoid arthritis

Interaction

  • ACE inhibitors
  • antacids & sucralfate
  • aspirin
  • diuretics
  • methotrexate
  • warfarin
  • selective serotonin reuptake inhibitors (SSRI)

Contraindications

  • known hypersensitivity to Naproxen
  • asthma
  • urticaria
  • allergic-type reactions after taking aspirin or other NSAIDs
  • perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • gastrointestinal
  • central nervous system
  • dermatological
  • cardiovascular
  • visual disturbances
  • hearing disturbances

Pregnancy & Lactation

  • adverse effect on the fetus
  • delay in parturition
  • premature closure of the ductus arteriosus
  • severe pulmonary hypertension in infants
  • excretion in breast milk
  • avoiding breastfeeding

Precautions & Warnings

  • renal effects
  • abnormal renal pathology
  • acute interstitial nephritis
  • hematuria
  • proteinuria
  • nephrotic syndrome
  • limited excretion by the kidneys
  • reduced kidney function caution
  • creatinine clearance monitoring
  • hepatic effects
  • jaundice

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • below 30°C temperature
  • protected from light & moisture
  • keep out of the reach of children

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