Roxenole 500 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 10.00 (30's pack: ৳ 300.00)

Medicine Details

Title

  • Naproxen & Esomeprazole Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Relief of Osteoarthritis symptoms
  • Relief of Rheumatoid arthritis symptoms
  • Relief of Ankylosing spondylitis symptoms
  • Decrease risk of developing gastric ulcers from NSAID

Dimensions

  • Standard tablet size

Color Options

  • White

Function

  • Relief of pain and inflammation
  • Proton pump inhibition for reduced gastric acidity

Materials

  • Naproxen
  • Esomeprazole
  • Magnesium
  • Enteric-coated core

Dosage

  • Adult dosage: 375 mg naproxen/20 mg esomeprazole
  • Adolescent dosage: variable based on weight range

Administration

  • Oral administration
  • Take at least 30 minutes before meals

Medicine Interaction

  • May reduce the antihypertensive effect of certain drugs
  • May increase risk of bleeding when used with warfarin
  • May interfere with absorption of certain drugs like Ketoconazole

Interaction with Food

  • Absorption affected by high-fat food

Contraindications

  • Hypersensitivity to components
  • History of allergic reactions to aspirin or NSAIDs
  • Use during peri-operative period for CABG surgery

Side Effects

  • Gastrointestinal side effects reduced by Esomeprazole
  • Possible risk of arterial thrombotic events
  • Possible oedema, hypertension, and cardiac failure

Pregnancy & Lactation

  • Not recommended during third trimester
  • Not recommended during breastfeeding
  • May impair female fertility

Precautions & Warnings

  • Avoid use with other NSAIDs
  • Minimize dosage and duration to reduce adverse effects
  • Risk factors for gastrointestinal complications
  • Increased risk for older individuals
  • Caution in patients with hypertension or heart failure
  • Risk of GI bleeding, ulceration, or perforation
  • Increased risk of gastrointestinal infections

Use in Special Populations

  • Use caution in elderly patients
  • Not recommended for patients with moderate to severe renal impairment
  • Close monitoring for patients with mild to moderate hepatic impairment

Overdose Effects

  • Symptoms related to Naproxen overdose
  • Symptoms related to Esomeprazole overdose
  • Management of overdose symptoms

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • NSAIDs

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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