Nebita 2.5 mg (Tablet)
Unit Price: ৳ 7.02 (5 x 10: ৳ 351.00)
Strip Price: ৳ 70.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Nebivolol hydrochloride |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Hypertension
- Treatment of essential hypertension
- Chronic heart failure (CHF)
- Treatment of stable mild and moderate chronic heart failure in elderly patients
Pharmacology
- β adrenergic receptor blocking agent
- β1 and β1 adrenergic receptors inhibition
- decreased heart rate
- decreased myocardia contractility
- suppression of renin activity
- vasodilation
- Pharmacokinetics
- Absorption and Distribution
- Metabolism and Excretion
- Interaction with Digoxin
- Interaction with Warfarin
Dosage & Administration
- Individualized dosing
- Recommended starting dose of 5 mg once daily
- Maximum dose of 40 mg
- No benefit from more frequent dosing regimen
Interaction
- Careful use with myocardial depressants
- Avoid combination with other β-blockers
- Caution with catecholamine-depleting drugs
- Use caution with CYP2D6 inhibitors
Contraindications
- Severe bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Decompensated cardiac failure
- Sick sinus syndrome without a permanent pacemaker
- Severe hepatic impairment
- Hypersensitivity to any component
Side Effects
- Headache
- Nausea
- Bradycardia
Precautions & Warnings
- Abrupt Cessation of Therapy
- Cardiac Failure
- Angina and Acute Myocardial Infarction
- Bronchospastic Diseases
- Anesthesia and Major Surgery
- Diabetes and Hypoglycemia
- Thyrotoxicosis
- Peripheral Vascular Disease
- Non-dihydropyridine Calcium Channel Blockers
Use in Special Populations
- Impaired Renal Function
- Impaired Hepatic Function
- Risk of Anaphylactic Reactions
Therapeutic Class
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children