Nepagen TS 0.3% (Ophthalmic Suspension)
5 ml drop: ৳ 250.00
Medicine Details
Category | Details |
---|---|
Generic | Nepafenac |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Treatment of post-operative ocular pain and inflammation including cataract surgery
- Inhibition of surgery induced miosis
- Prevention of post-operative cystoid macular edema (CME)
- Post-operative pain and inflammation associated with cataract surgery
Pharmacology
- Nepafenac is a nonsteroidal anti-inflammatory prodrug (NSAID)
- Penetrates the cornea
- Converted by ocular tissue hydrolase to Amfenac
- Inhibits the action of cyclooxygenase enzyme
- Required for prostaglandin synthesis
Dosage & Administration
- Nepafenac 0.1% Sterile Ophthalmic Suspension:
- Instill 1 drop 3 times daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period
- Instill 1 drop 3 times daily 1 day before surgery & on the day of surgery
- Instill 1 drop 3 times daily 1 day before surgery and continued on the day of surgery and through the first 6 weeks of the post-operative period
- Nepafenac 0.3% Sterile Ophthalmic Suspension:
- Instill 1 drop once daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period
- Additional drop should be administered 30 to 120 minutes prior to surgery
Contraindications
- Patients with previously demonstrated hypersensitivity to any of the ingredients in the formulation or to other NSAIDs
Side Effects
- Foreign body sensation
- Lid margin crusting
- Ocular discomfort
- Ocular hyperemia
Pregnancy & Lactation
- Use in pregnancy: There are no adequate and well-controlled studies in pregnant women
- Nepafenac should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
- Use in lactation: It is not known whether this drug is excreted in human milk
- Caution should be exercised when Nepafenac ophthalmic suspension is administered to a nursing mother
Precautions & Warnings
- Use with caution in patients with known bleeding tendencies or who are receiving medications which may prolong bleeding time
Use in Special Populations
- Use in children: Safety and effectiveness in pediatric patients below 18 years of age have not been established
- No overall differences in safety or effectiveness observed between elderly and younger patients
Therapeutic Class
- Ophthalmic Non-Steroid drugs
Related Brands
- Nevan 0.1% (Ophthalmic Suspension) - aristopharma-ltd
- Nevan TS 0.3% (Ophthalmic Suspension) - aristopharma-ltd
- Opanac 0.1% (Ophthalmic Suspension) - beximco-pharmaceuticals-ltd
- Optafenac 0.1% (Ophthalmic Suspension) - popular-pharmaceuticals-ltd
- Optafenac TS 0.3% (Ophthalmic Suspension) - popular-pharmaceuticals-ltd