Niz 500 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 6: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Nitazoxanide
Company Ethical drugs limited
Also available as
Niz 100 mg suspension

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Synthetic antiprotozoal agent for oral administration
  • Interference with Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
  • Active in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
  • Active in inhibiting the growth of trophozoites of Giardia lamblia

Dosage & Administration

  • 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days for age 1-3 years
  • 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days for age 4-11 years
  • 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days for age 12 years or above
  • Recommended to be administered with food

Interaction

  • Highly bound to plasma protein
  • Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

  • Frequent side effects: abdominal pain, vomiting, headache
  • Rare side effects: nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine

Pregnancy & Lactation

  • US FDA pregnancy category: B
  • No adequate and well-controlled studies in pregnant women
  • Drug excreted in human milk
  • Caution when administered during lactation

Precautions & Warnings

  • Administered with caution to patients with hepatic & biliary disease
  • Administered with caution to patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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