Alinix 500 mg (Tablet)
Unit Price: ৳ 10.00 (5 x 6: ৳ 300.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Nitazoxanide |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of diarrhea caused by Cryptosporidium parvum
- Treatment of diarrhea caused by Giardia lamblia
- Treatment of diarrhea caused by Entamoeba histolytica
Pharmacology
- Nitazoxanide is a synthetic antiprotozoal agent for oral administration
- Interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependent electron transfer reaction
- Essential for anaerobic energy metabolism of the protozoa
- Active in vitro in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
- Active in vitro in inhibiting the growth of trophozoites of Giardia lamblia
Dosage & Administration
- For age 1-3 years: 1 teaspoonfull or 5 ml suspension every 12 hours for 3 days
- For age 4-11 years: 2 teaspoonfulls or 10 ml suspension every 12 hours for 3 days
- For age 12 years or above: 5 teaspoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
- Recommended to be administered with food
Interaction
- Highly bound to plasma protein
- Exercise caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index
Contraindications
- Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation
Side Effects
- Common side effects: abdominal pain, vomiting, headache (mild and transient)
- Rare side effects: nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine
Pregnancy & Lactation
- US FDA pregnancy category: B
- No adequate and well-controlled studies in pregnant women
- Caution should be exercised during pregnancy
- Nitazoxanide excreted in human milk, caution during lactation
Precautions & Warnings
- Administer with caution to patients with hepatic & biliary disease
- Administer with caution to patients with renal disease
Therapeutic Class
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children