Dianide 500 mg (Tablet)
Unit Price: ৳ 10.07 (2 x 3: ৳ 60.43)
Strip Price: ৳ 30.22
Medicine Details
Category | Details |
---|---|
Generic | Nitazoxanide |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Treatment of diarrhea caused by Cryptosporidium parvum
- Treatment of diarrhea caused by Giardia lamblia
- Treatment of diarrhea caused by Entamoeba histolytica
Pharmacology
- Synthetic antiprotozoal agent for oral administration
- Interferes with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
- Inhibits the growth of sporozoites and oocyst of Cryptosporidium parvum
- Inhibits the growth of trophozoites of Giardia lamblia
Dosage & Administration
- Age 1-3 years: 1 teaspoonful or 5 ml suspension every 12 hours for 3 days
- Age 4-11 years: 2 teaspoonfuls or 10 ml suspension every 12 hours for 3 days
- Age 12 years or above: 5 teaspoonfuls (25 ml) suspension or 1 tablet every 12 hours for 3 days
- Recommended to be administered with food
Interaction
- Highly bound to plasma protein
- Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index
Contraindications
- Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation
Side Effects
- Abdominal pain
- Vomiting
- Headache
- Nausea
- Anorexia
- Flatulence
- Increased appetite
- Enlarged salivary glands
- Increased creatinine & SGPT level
- Pruritus
- Rhinitis
- Sweating
- Dizziness
- Discolored urine
- Mild and transient in nature
Pregnancy & Lactation
- US FDA pregnancy category of Nitazoxanide is B
- No adequate and well-controlled studies in pregnant women
- Excreted in human milk
- Caution should be exercised when administered during lactation
Precautions & Warnings
- Administer with caution to patients with hepatic & biliary disease
- Administer with caution to patients with renal disease
Therapeutic Class
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children