Olanza 10 mg (Tablet)
Unit Price: ৳ 4.52 (5 x 10: ৳ 226.00)
Strip Price: ৳ 45.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Olanzapine |
| Company | Albion laboratories limited |
| Also available as |
Product Title
- Olanzapine Tablets
Categories
- Antipsychotic
- Neuroleptic
- Psychosis Treatment
Description
- Olanzapine is indicated for the acute and maintenance treatment of schizophrenia and related psychoses where positive and/or negative symptoms are prominent. It is also used for the treatment of acute manic or mixed episodes in bipolar disorder.
Color Options
- White
Function
- Treatment of schizophrenia
- Treatment of manic or mixed episodes in bipolar disorder
- Reduction of positive and negative psychotic symptoms
Active Ingredients
- Olanzapine
Dosage Form
- Tablet
Dosage Strength
- 5mg
- 10mg
- 15mg
- 20mg
Mode of Action
- Affinities for serotonin, dopamine, cholinergic, adrenergic, and histamine receptors
- 5HT2 and dopamine antagonism
Pharmacokinetics
- Well absorbed after oral administration
- Reaches peak plasma concentration within 5 to 8 hours
- Absorption not affected by food
Administration
- Can be given without regard to meals
- Gradual tapering of the dose should be considered while discontinuing
Interaction
- May antagonize the effects of levodopa and dopamine agonists
- Influenced by CYP1A2 inducers and inhibitors
- Carbamazepine may increase clearance
Contraindications
- Known hypersensitivity to any ingredient
- Narrow-angle glaucoma
Side Effects
- Somnolence
- Weight gain
- Increased appetite
- Elevated glucose and triglyceride levels
- Dizziness
- Akathisia
- Orthostatic hypotension
Pregnancy and Lactation
- Use in pregnancy only if benefits justify the potential risk
- No reports of teratogenicity
- Avoid breastfeeding while taking Olanzapine
Precautions and Warnings
- Caution in patients with history of seizures or low leukocyte/neutrophil counts
- Cautious use in patients with impaired hepatic function
- Caution about operating hazardous machinery
Special Populations
- Not studied in subjects under 18 years of age
- Elderly patients: starting dose 5 mg/day
- Patients with hepatic or renal impairment: starting dose 5 mg/day
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children