Orbas 40 mg (Tablet)

Unit Price: ৳ 15.04 (3 x 10: ৳ 451.20)
Strip Price: ৳ 150.40

Medicine Details

Category Details
Generic Olmesartan medoxomil
Company Acme laboratories ltd
Also available as
Orbas 20 mg tablet

Indications

  • Treatment of hypertension
  • May be used alone or in combination with other antihypertensive agents

Pharmacology

  • Blocks vasoconstrictor effects of angiotensin II
  • Selective blockade of AT 1 receptor in vascular smooth muscle
  • Does not inhibit ACE (kininase II)
  • Blocks negative regulatory feedback of angiotensin II on renin secretion

Dosage & Administration

  • Usual recommended starting dose of 20 mg once daily
  • Further reduction in blood pressure after 2 weeks may increase dose to 40 mg
  • Doses above 40 mg do not appear to have a greater effect

Interaction

  • No significant drug interactions reported with digoxin or warfarin
  • Bioavailability not significantly altered by antacids
  • No interaction with cytochrome P450 system

Contraindications

  • Hypersensitivity to any component

Side Effects

  • Well tolerated with incidence of adverse reactions similar to placebo
  • Most common adverse reaction: dizziness

Pregnancy & Lactation

  • Discontinue drug when pregnancy is detected
  • Can cause injury and death to developing fetus when used during second and third trimesters
  • Undetermined excretion in human milk

Precautions & Warnings

  • May cause changes in renal function
  • May be associated with oliguria and/or progressive azotemia

Overdose Effects

  • No experience of overdose reported
  • Likely effects include hypotension and tachycardia

Therapeutic Class

  • Angiotensin-ll receptor blocker

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula : C29H30N6O6
  • Chemical Structure Image : Provided

Common Questions about Orbas 40 mg Tablet

  • Uses include treatment of high blood pressure
  • Average time for peak effect: 1 day to 1 week
  • Generally used once or twice a day
  • Oral consumption recommended

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