Dianide 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 35.24

Medicine Details

Category Details
Generic Nitazoxanide
Company General pharmaceuticals ltd
Also available as
Dianide 500 mg tablet

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Synthetic antiprotozoal agent for oral administration
  • Interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
  • Inhibition of the growth of sporozoites and oocyst of Cryptosporidium parvum and trophozoites of Giardia lamblia

Dosage & Administration

  • Age 1-3 years: 1 tea-spoonful or 5 ml suspension every 12 hours for 3 days
  • Age 4-11 years: 2 tea-spoonfuls or 10 ml suspension every 12 hours for 3 days
  • Age 12 years or above: 5 tea-spoonfuls (25 ml) suspension or 1 tablet every 12 hours for 3 days
  • Recommended to be administered with food

Interaction

  • Highly bound to plasma protein
  • Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

  • Abdominal pain
  • Vomiting
  • Headache
  • Mild and transient nature of side effects
  • Rare side effects: nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Excreted in human milk
  • Caution during lactation

Precautions & Warnings

  • Administered with caution to patients with hepatic & biliary disease
  • Administered with caution to patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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