Ransys 10 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olmesartan medoxomil |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Therapeutic Class
- Angiotensin-ll receptor blocker
Indications
- Treatment of hypertension
- May be used alone or in combination with other antihypertensive agents
Pharmacology
- Blocks vasoconstrictor effects of angiotensin II
- Inhibits negative feedback of angiotensin II on renin secretion
Dosage & Administration
- Usual recommended starting dose: 20 mg once daily
- Dose may be increased to 40 mg for further reduction in blood pressure
- No initial dosage adjustment recommended for elderly patients
- No initial dosage adjustment recommended for patients with moderate to marked renal impairment
- May be administered with or without food
Interaction
- No significant drug interactions reported with digoxin or warfarin
- Bioavailability not significantly altered by antacids
- Not metabolized by the cytochrome P450 system
- Potential deterioration of renal function when co-administered with NSAIDs
- Antihypertensive effect may be attenuated by NSAIDs
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Well tolerated with an incidence of adverse reactions similar to placebo
- Incidence of adverse reactions not dose related
- Most common adverse reaction: dizziness
- Other adverse reactions at more than 1% incidence: back pain, bronchitis, increased creatine phosphokinase, diarrhea, headache, hematuria, hyperglycemia, hypertriglyceridemia, influenza-like symptoms, pharyngitis, rhinitis, and sinusitis
- Incidence of cough similar to placebo
Pregnancy & Lactation
- Discontinue when pregnancy is detected
- Can cause injury or death to developing fetus when used during second and third trimesters
- Potential excretion in human milk
Precautions & Warnings
- May cause changes in renal function
- Association with oliguria, progressive azotemia, acute renal failure, and death in susceptible individuals
Overdose Effects
- No experience of overdose reported
- Most likely effects: hypotension and tachycardia
- Management may include gastric lavage, induction of emesis, and cardiovascular system support
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C29H30N6O6
Common Questions
- Uses: Treatment of high blood pressure
- Onset of peak effect: 1 day to 1 week
- Frequency of use: Generally once or twice a day
- Instructions for storage and disposal
Common Tips
- Take at the same time daily to help remember
- May cause dizziness initially
- Regular tests for monitoring urea, creatinine, and potassium levels
- Avoid taking anti-inflammatory medicines without consulting doctor
- May increase potassium levels in blood
- Avoid if pregnant or breastfeeding
- Do not discontinue suddenly without consulting doctor