Abetis Plus 40 mg+12.5 mg (Tablet)

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)

Strip Price: ৳ 180.00

Medicine Details

Category	Details
Generic	Olmesartan medoxomil hydrochlorothiazide
Company	Aci limited
Also available as	Abetis plus 20 mg tablet

Indications

Treatment of hypertension

Pharmacology

Olmesartan blocks vasoconstrictor effects of angiotensin-II
Hydrochlorothiazide is a thiazide diuretic affecting renal tubular mechanisms

Dosage & Administration

Usual starting dose of 20/12.5 mg once daily
Dose titration based on blood pressure response

Interaction

No significant drug interactions reported for Olmesartan
Hydrochlorothiazide may interact with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, corticosteroids, lithium

Contraindications

Hypersensitivity to any component of the product
Anuria or hypersensitivity to sulfonamide-derived drugs

Side Effects

Nausea
Headache
Dizziness
Hyperuricemia
Upper respiratory tract infection
Urinary tract infection
Chest pain
Back pain
Peripheral edema
Abdominal pain
Dyspepsia
Gastroenteritis
Diarrhea

Pregnancy & Lactation

Safety and effectiveness not established, should be discontinued during pregnancy and lactation

Precautions & Warnings

Periodic determination of serum electrolytes
Hyperuricemia
Impaired renal function

Use in Special Populations

Renal impairment: therapy depends on creatinine clearance
Hepatic impairment: no dosage adjustment necessary
Paediatric use: safety and effectiveness not established
Geriatric use: cautious dose selection

Overdose Effects

Olmesartan overdose likely manifests as hypotension and tachycardia
Hydrochlorothiazide overdose may cause electrolyte depletion and dehydration

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Store in a cool and dry place
Protect from light and moisture
Keep out of reach of children

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