Omixen 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00

Medicine Details

Category Details
Generic Omeprazole
Company Allied pharmaceuticals ltd

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulce
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral dosage for different conditions
  • IV Injection for prophylaxis of acid aspiration
  • IV Injection for duodenal ulcer, gastric ulcer, or reflux oesophagitis
  • IV Injection for Zollinger-Ellison syndrome
  • Paediatric dosage in severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for reconstitution and administration of IV injection

Interaction

  • Potential interactions with ketoconazole
  • Metabolism through cytochrome P450
  • Interactions with diazepam, phenytoin, warfarin, and clarithromycin
  • No evidence of interaction with certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to omeprazole
  • Exclusion of malignancy before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus
  • Diarrhea and headache
  • Gastrointestinal reactions
  • Neurological reactions
  • Mental confusion, agitation, depression, and hallucinations
  • Arthritic and myalgic symptoms
  • Hepatic and hematologic reactions

Pregnancy & Lactation

  • No adverse effects indicated on pregnancy or fetus
  • Use during pregnancy indicated
  • No information available on passage into breast milk
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis with long-term use
  • Potential methotrexate toxicities with concomitant use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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