Nidor 500 mg (Tablet)
Unit Price: ৳ 10.04 (3 x 10: ৳ 301.20)
Strip Price: ৳ 100.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Nitazoxanide |
| Company | Pharmasia limited |
| Also available as |
Indications
- Treatment of diarrhea caused by Cryptosporidium parvum
- Treatment of diarrhea caused by Giardia lamblia
- Treatment of diarrhea caused by Entamoeba histolytica
Pharmacology
- Synthetic antiprotozoal agent
- Oral administration
- Interference with Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
- Essential for anaerobic energy metabolism of the protozoa
- Active in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
- Active in inhibiting the growth of trophozoites of Giardia lamblia
Dosage & Administration
- Age 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days
- Age 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days
- Age 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
- Recommended to be administered with food
Interaction
- Highly bound to plasma protein
- Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index
Contraindications
- Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation
Side Effects
- Abdominal pain
- Vomiting
- Headache
- Mild and transient nature of side effects
- Rare side effects including nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine
Pregnancy & Lactation
- US FDA pregnancy category B
- No adequate and well-controlled studies in pregnant women
- Drug should be used during pregnancy only if clearly needed
- Excreted in human milk
- Caution should be exercised when administered during lactation
Precautions & Warnings
- Administered with caution to patients with hepatic & biliary disease
- Administered with caution to patients with renal disease
Therapeutic Class
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children