Gap 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Euro pharma ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Omeprazole, a substituted benzimidazole, is an inhibitor of gastric acid secretion.
Dosage
- 20 mg once daily for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
- 20 mg once daily for 4 weeks, continued for further 4 weeks, if not fully healed
- 20 mg once daily for 4 weeks, continued for further 4-8 weeks, if not fully healed
- 10-20 mg daily for long-term management of acid reflux disease
- 10-20 mg once daily for 2-4 weeks in acid-related dyspepsia
- 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
- Initial dose of 60 mg once daily for Zollinger-Ellison syndrome
- Omeprazole 20 mg twice daily in association with antimicrobial agents for Helicobacter pylori eradication regimen
- 10-20 mg once daily for 4-12 weeks in severe ulcerating reflux esophagitis for pediatric use
Administration
- IV injection given slowly as an intravenous injection
- IV infusion over a period of 20-30 minutes or more for Omeprazole IV infusion
Interaction
Reduced absorption of ketoconazole, delayed elimination of diazepam, phenytoin, and warfarin, increased plasma concentrations of Omeprazole and clarithromycin
Contraindications
Known hypersensitivity to Omeprazole, suspicion of gastric ulcer malignancy
Side Effects
- Skin rash, urticaria, pruritus, photosensitivity
- Diarrhea, headache, constipation, nausea/vomiting
- Dry mouth, stomatitis, candidiasis
- Dizziness, light headedness, somnolence
- Reversible mental confusion, agitation, depression
- Arthritic and myalgic symptoms
- Blurred vision, taste disturbance, peripheral edema
- Increased liver enzymes
Pregnancy & Lactation
Safe use during pregnancy, discontinuation of breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis with long-term use
- Concomitant use with methotrexate may lead to toxicities
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat, Keep out of the reach of children