Neome 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Fnf pharmaceuticals ltd |
Indications
- Treatment of gastric and duodenal ulcer
- Treatment of NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Treatment of gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Treatment of acid-related dyspepsia
- Treatment of severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Treatment of Zollinger-Ellison syndrome
- Treatment of Helicobacter pylori-induced peptic ulcer
Pharmacology
- Omeprazole as an inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
- Return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Oral dosage for various conditions
- IV injection dosage for various conditions
- Pediatric use dosage for severe ulcerating reflux esophagitis
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
Interaction
- Impact on the absorption of ketoconazole
- Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin
- Monitoring and potential dose adjustment for warfarin or phenytoin
- Increased plasma concentrations during concomitant administration with clarithromycin
- No evidence of interaction with phenacetin, theophylline, caffeine, and more
Contraindications
- Known hypersensitivity to omeprazole
- Suspicion of gastric ulcer with possibility of malignancy
Side Effects
- Mild and reversible adverse reactions
- Reported skin rash, urticaria, pruritus, photosensitivity, and more
- Gastrointestinal reactions such as diarrhea, headache, constipation, and more
- Neurological symptoms like paraesthesia, dizziness, and more
- Hematological and hepatic side effects
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child based on studies
- Usage during pregnancy is acceptable
- No information available on passage into breast milk or effects on the neonate
- Discontinuation of breastfeeding if essential use of omeprazole
Precautions & Warnings
- Avoid concomitant use of clopidogrel and omeprazole
- Potential association of PPI therapy with increased risk for osteoporosis-related fractures
- Atrophic gastritis in long-term treatment
- Concomitant use with methotrexate may lead to toxicities
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children