Neome 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00

Medicine Details

Category Details
Generic Omeprazole
Company Fnf pharmaceuticals ltd

Indications

  • Treatment of gastric and duodenal ulcer
  • Treatment of NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Treatment of gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Treatment of severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Treatment of Zollinger-Ellison syndrome
  • Treatment of Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Omeprazole as an inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Return of secretory activity over 3 to 5 days after discontinuation

Dosage

  • Oral dosage for various conditions
  • IV injection dosage for various conditions
  • Pediatric use dosage for severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion

Interaction

  • Impact on the absorption of ketoconazole
  • Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin
  • Monitoring and potential dose adjustment for warfarin or phenytoin
  • Increased plasma concentrations during concomitant administration with clarithromycin
  • No evidence of interaction with phenacetin, theophylline, caffeine, and more

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspicion of gastric ulcer with possibility of malignancy

Side Effects

  • Mild and reversible adverse reactions
  • Reported skin rash, urticaria, pruritus, photosensitivity, and more
  • Gastrointestinal reactions such as diarrhea, headache, constipation, and more
  • Neurological symptoms like paraesthesia, dizziness, and more
  • Hematological and hepatic side effects

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus/newborn child based on studies
  • Usage during pregnancy is acceptable
  • No information available on passage into breast milk or effects on the neonate
  • Discontinuation of breastfeeding if essential use of omeprazole

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and omeprazole
  • Potential association of PPI therapy with increased risk for osteoporosis-related fractures
  • Atrophic gastritis in long-term treatment
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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