G-Omeprazole 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 3.45 (10 x 10: ৳ 345.00)
Strip Price: ৳ 34.50

Medicine Details

Category Details
Generic Omeprazole
Company Gonoshasthaya pharma ltd
Also available as
G omeprazole 40 mg injection

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis for patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Return of secretory activity over 3 to 5 days after discontinuation

Dosage

  • Various dosage regimens for different conditions
  • Oral and intravenous administration
  • Dosage adjustments for severe or recurrent cases
  • Recommended dosage for pediatric use

Administration

  • Directions for use of IV injection
  • Directions for use of IV infusion
  • Instructions for reconstitution and administration

Interactions

  • Potential interaction with ketoconazole affecting absorption
  • Metabolism in the liver through cytochrome P450
  • Possible delay in elimination of diazepam, phenytoin, and warfarin
  • Increased plasma concentrations during concurrent administration

Contraindications

  • Known hypersensitivity to omeprazole
  • Exclusion of malignancy in suspected gastric ulcer before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhoea, headache, constipation, nausea/vomiting
  • Dizziness, feeling faint, somnolence, insomnia
  • Arthritic and myalgic symptoms
  • Potential hepatic and hematologic effects

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus
  • Lack of information on passage into breast milk
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted in long-term use
  • Potential interaction with methotrexate

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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