G-Omeprazole 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 3.45 (10 x 10: ৳ 345.00)
Strip Price: ৳ 34.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Gonoshasthaya pharma ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis for patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect within two hours
- Inhibition of secretion lasts up to 72 hours
- Return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Various dosage regimens for different conditions
- Oral and intravenous administration
- Dosage adjustments for severe or recurrent cases
- Recommended dosage for pediatric use
Administration
- Directions for use of IV injection
- Directions for use of IV infusion
- Instructions for reconstitution and administration
Interactions
- Potential interaction with ketoconazole affecting absorption
- Metabolism in the liver through cytochrome P450
- Possible delay in elimination of diazepam, phenytoin, and warfarin
- Increased plasma concentrations during concurrent administration
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy in suspected gastric ulcer before treatment
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhoea, headache, constipation, nausea/vomiting
- Dizziness, feeling faint, somnolence, insomnia
- Arthritic and myalgic symptoms
- Potential hepatic and hematologic effects
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus
- Lack of information on passage into breast milk
- Discontinuation of breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted in long-term use
- Potential interaction with methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children