Omilant 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.02 (100's pack: ৳ 502.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Guardian healthcare ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- 20 mg once daily for duodenal ulceration
- 40 mg daily for severe or recurrent cases of gastric ulceration
- 10-20 mg daily for prevention of relapse in duodenal ulcer
- 20 mg once daily for NSAID-associated duodenal or gastric ulcer
- 20-40 mg daily for Gastro-esophageal reflux disease
- 10-20 mg daily for Long-term management of acid reflux disease
Mode of Administration
- Oral administration
- Intravenous injection
Route of Administration
- Oral
- Intravenous
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin elimination
- Increased plasma concentrations during concomitant administration with clarithromycin
Contraindications
- Known hypersensitivity to omeprazole
Side Effects
- Skin rash
- Urticaria
- Pruritus
- Photosensitivity
- Diarrhea
- Headache
- Constipation
- Nausea/vomiting
- Dizziness
- Dry mouth
- Abdominal pain
Pregnancy & Lactation
- Safe for use during pregnancy
- Discontinue breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
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