Peptral 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.03 (5 x 6: ৳ 270.90)
Strip Price: ৳ 54.18

Medicine Details

Category Details
Generic Omeprazole
Company Labaid pharma ltd
Also available as
Peptral 20 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Secretory activity returns gradually over 3 to 5 days after discontinuation

Dosage

  • Dosage for gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen
  • Dosage for pediatric use in severe ulcerating reflux esophagitis
  • Dosage for IV injection in various conditions

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Preparation of IV solution
  • Duration of intravenous administration
  • Precautions for IV administration

Interaction

  • Interaction with ketoconazole
  • Metabolism through cytochrome P450
  • Potential interactions with diazepam, phenytoin, warfarin, clarithromycin, and antimicrobial agents
  • Effects on absorption of other medications
  • Effects on plasma concentrations of other drugs

Contraindications

  • Known hypersensitivity to the product
  • Possibility of malignancy in gastric ulcer cases

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity and bullous eruption
  • Diarrhea and headache
  • Gastrointestinal reactions
  • Neurological symptoms
  • Mental and psychological effects
  • Musculoskeletal symptoms
  • Other reported adverse reactions

Pregnancy & Lactation

  • Safety during pregnancy
  • Lactation considerations
  • Use in children & adolescents

Precautions & Warnings

  • Concomitant use of clopidogrel
  • Risk for osteoporosis-related fractures
  • Atrophic gastritis effects
  • Concomitant use with methotrexate

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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