Perizol 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (40's pack: ৳ 320.00)

Medicine Details

Category Details
Generic Omeprazole
Company Leon pharmaceuticals ltd
Also available as
Perizol 20 mg capsule

Title

  • Perizol

Categories

  • Medicine
  • Gastric Ulcer Treatment
  • Proton Pump Inhibitor

Description

  • Indicated for various gastrointestinal conditions
  • Inhibits gastric acid secretion
  • Diverse dosage forms and regimens for different conditions
  • Detailed administration directions for IV injection and infusion
  • Interacts with other medications
  • List of contraindications
  • Potential side effects
  • Information on use during pregnancy and lactation
  • Precautions and warnings
  • Storage conditions

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Treatment of gastric and duodenal ulcer
  • Prophylaxis of acid aspiration during general anesthesia
  • Management of acid reflux disease
  • Eradication of Helicobacter pylori-induced peptic ulcer
  • Treatment of gastro-esophageal reflux disease
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Management of acid-related dyspepsia
  • Treatment of severe ulcerating reflux esophagitis
  • Recommended for Zollinger-Ellison syndrome

Materials

  • Omeprazole
  • Lyophilized powder
  • Water for injection
  • Saline for infusion
  • 5% Dextrose for infusion

Technical Specifications

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect occurs within one hour
  • Inhibition of secretion lasts up to 72 hours
  • Secretory activity returns gradually over 3 to 5 days after discontinuation

Design Elements

  • N/A

Usability Features

  • Oral and IV dosage forms
  • Administration as intravenous injection and infusion
  • Slow intravenous injection
  • Avoid concomitant use with certain medications

Interactions

  • Can affect absorption of ketoconazole
  • Metabolized in the liver through cytochrome P450
  • Can delay elimination of diazepam, phenytoin, and warfarin
  • Can affect plasma concentrations of other medications
  • No interaction with certain drugs

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspicion of gastric ulcer where malignancy is not excluded

Side Effects

  • Mild and reversible adverse reactions
  • Reports of skin rash, urticaria, and pruritus
  • Reports of photosensitivity, bullous eruption, and erythema multiforme
  • Reports of diarrhea, headache, constipation, nausea/vomiting, and abdominal pain
  • Reports of dry mouth, stomatitis, and candidiasis
  • Reports of dizziness, light headedness, and feeling faint
  • Reports of somnolence, insomnia, and vertigo
  • Reports of reversible mental confusion, agitation, depression, and hallucinations
  • Reports of arthritic and myalgic symptoms
  • Reports of blurred vision, taste disturbance, and peripheral edema
  • Reports of increased sweating, gynaecomastia, and hematological effects
  • Reports of hepatic and renal effects

Pregnancy & Lactation

  • No adverse effects on pregnancy or on the health of the fetus/newborn child
  • Use during pregnancy can be considered
  • No information available on passage into breast milk or effects on the neonate
  • Breastfeeding discontinuation if essential use of Omeprazole

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally with long-term use
  • Potential interaction with methotrexate

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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