Onelock 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (6 x 10: ৳ 360.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	One pharma ltd
Also available as	Onelock 40 mg capsule

Indications

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

Pharmacology

Inhibitor of gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell. Onset of antisecretory effect occurs within one hour, with the maximum effect within two hours and inhibition of secretion lasts up to 72 hours.

Dosage

20 mg once daily for 4-8 weeks in gastric ulceration
10-40 mg daily for various conditions
Recommended dose in various gastric conditions
Different doses for pediatric use
40 mg IV injection for prophylaxis of acid aspiration
60 mg IV injection for Zollinger-Ellison syndrome
20 mg twice daily for Helicobacter pylori eradication regimen

Administration

IV Injection directions
IV Infusion directions
Reconstitution and usage instructions for IV injection and infusion

Interaction

Interactions with ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, phenacetin, theophylline, caffeine, and other drugs. No interactions with alcohol or certain NSAIDs

Contraindications

Contraindicated in patients with known hypersensitivity to omeprazole. Possibility of malignancy should be excluded before treatment.

Side Effects

Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, and erythema multiforme
Diarrhea and headache
Gastrointestinal reactions
Dizziness, somnolence, and insomnia
Mental confusion, agitation, and depression
Arthritic and myalgic symptoms
Blood and liver-related side effects
Other isolated cases of side effects

Pregnancy & Lactation

No adverse effects of Omeprazole on pregnancy or fetus/newborn child. Use during pregnancy is acceptable. Discontinue breastfeeding if essential.

Precautions & Warnings

Avoid concomitant use with clopidogrel
Potential association with increased risk for osteoporosis-related fractures
Atrophic gastritis in long-term use
Potential methotrexate toxicities with concomitant use of PPIs

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.