Stosec 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.00

Medicine Details

Category Details
Generic Omeprazole
Company Osl pharma limited
Also available as
Stosec 20 mg capsule

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis for patients with a history of NSAID-associated duodenal and gastric ulcer
  • Treatment of gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Treatment of severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Treatment of Zollinger-Ellison syndrome
  • Treatment of Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Substituted benzimidazole
  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Gradual return of secretory activity over 3 to 5 days upon discontinuation

Dosage

  • Oral administration for various conditions
  • Prophylaxis of acid aspiration via IV injection

Administration

  • Instruction for IV Injection administration
  • Instruction for IV Infusion administration
  • Guidance for reconstituted solution usage

Interaction

  • Reduction in ketoconazole absorption during treatment
  • Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin
  • Monitoring and potential dose adjustment for warfarin or phenytoin during concomitant treatment
  • Increase in plasma concentrations of Stosec and clarithromycin during concurrent administration
  • No interaction with phenacetin, theophylline, caffeine, and more

Contraindications

  • Known hypersensitivity to Omeprazole
  • Suspected gastric ulcer should exclude possibility of malignancy before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Reported reactions include skin rash, urticaria, pruritus, photosensitivity, diarrhea, headache, constipation, nausea/vomiting, and more

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus/newborn child in epidemiological studies
  • Suitable for use during pregnancy, no available information on passage into breast milk
  • Discontinuation of breastfeeding if essential use of Omeprazole is considered

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Stosec
  • Observational association of PPI therapy with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term treatment with Stosec
  • Potential for methotrexate toxicities with concomitant use of PPIs

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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