Nitanid 100 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 50.20

Medicine Details

Category Details
Generic Nitazoxanide
Company Drug international ltd
Also available as
Nitanid 500 mg tablet

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Synthetic antiprotozoal agent for oral administration
  • Believed to interfere with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme
  • Essential for anaerobic energy metabolism of the protozoa
  • Active in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
  • Active in inhibiting the growth of trophozoites of Giardia lamblia

Dosage & Administration

  • 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days
  • 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days
  • 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
  • Recommended to be administered with food

Interaction

  • Highly bound to plasma protein
  • Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

  • Abdominal pain
  • Vomiting
  • Headache
  • Nausea (rare)
  • Anorexia (rare)
  • Flatulence (rare)
  • Increased appetite (rare)
  • Enlarged salivary glands (rare)
  • Increased creatinine & SGPT level (rare)
  • Pruritus (rare)
  • Rhinitis (rare)
  • Sweating (rare)
  • Dizziness (rare)
  • Discolored urine (rare)

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Usage during pregnancy only if clearly needed
  • Excreted in human milk
  • Caution when administered during lactation

Precautions & Warnings

  • To be administered with caution to patients with hepatic & biliary disease
  • To be administered with caution to patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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