Prazomax 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (100's pack: ৳ 400.00)

Medicine Details

Category Details
Generic Omeprazole
Company Jenphar bangladesh ltd
Also available as
Prazomax 40 mg capsule

Title

  • Prazomax

Category

  • Proton Pump Inhibitor

Indications

  • Treatment of Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease management
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia management
  • Severe ulcerating reflux esophagitis treatment
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome treatment
  • Helicobacter pylori-induced peptic ulcer treatment

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase enzyme system in the gastric parietal cell
  • Onset of the antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral dosage for various conditions
  • IV Injection dosage for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux esophagitis, Zollinger-Ellison syndrome
  • IV Infusion instructions

Administration

  • Directions for IV Injection use
  • Directions for IV Infusion use

Interaction

  • Decreased intragastric acidity affecting the absorption of ketoconazole
  • Metabolized in the liver through cytochrome P450
  • Potential interaction with drugs like ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole
  • No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, antacids, piroxicam, diclofenac, naproxen

Contraindications

  • Known hypersensitivity
  • Suspicion of gastric ulcer without excluding the possibility of malignancy

Side Effects

  • Skin rash, urticaria, pruritus
  • Photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia
  • Diarrhea, headache, constipation, nausea/vomiting, flatulence, abdominal pain
  • Dry mouth, stomatitis, candidiasis
  • Paraesthesia, dizziness, lightheadedness, faintness
  • Somnolence, insomnia, vertigo
  • Reversible mental confusion, agitation, depression, hallucinations
  • Arthritic and myalgic symptoms
  • Blurred vision, taste disturbance, peripheral edema, increased sweating, gynaecomastia, hematological disorders, anaphylactic shock, malaise, fever, bronchospasm, hepatic disorders

Pregnancy & Lactation

  • No adverse effects on pregnancy or the health of the fetus/newborn child
  • Can be used during pregnancy
  • No information available on its passage into breast milk

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term use
  • Potential methotrexate toxicities with concomitant use

Storage Conditions

  • Keep in a dry place, away from light and heat, and out of the reach of children

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