SB-Omec 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (100's pack: ৳ 500.00)

Medicine Details

SB-Omec is indicated for the treatment of various conditions including gastric and duodenal ulcers, gastro-esophageal reflux disease, Zollinger-Ellison syndrome, Helicobacter pylori-induced peptic ulcers, acid-related dyspepsia, and severe ulcerating reflux esophagitis.
It is an inhibitor of gastric acid secretion.
The dosage varies for different indications, with recommended oral and IV dosages for different conditions and patient groups.
It should be administered intravenously as an injection or infusion, with specific instructions for use.
There are certain drug interactions to be aware of, and contraindications to consider, including hypersensitivity to Omeprazole.
Common side effects include skin rash, urticaria, pruritus, photosensitivity, diarrhea, headache, constipation, nausea/vomiting, and abdominal pain.
Omeprazole is considered safe for use during pregnancy, but caution is advised during lactation.
There are precautions and warnings regarding the concomitant use of clopidogrel, risk of osteoporosis-related fractures, atrophic gastritis, and interactions with methotrexate.
The product should be stored in a dry place away from light and heat, and kept out of the reach of children.

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

Inhibitor of gastric acid secretion
Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell
Onset of antisecretory effect occurs within one hour of oral administration
Maximum effect occurs within two hours
Inhibition of secretion lasts up to 72 hours
Gradual return of secretory activity over 3 to 5 days after discontinuation

Dosage varies for different indications
Oral dosage for benign gastric and duodenal ulcer, NSAID-associated duodenal or gastric ulcer, gastro-esophageal reflux disease, long-term management of acid reflux disease, acid-related dyspepsia, prophylaxis of acid aspiration, Zollinger-Ellison syndrome, Helicobacter pylori eradication regimen, and pediatric use in severe ulcerating reflux esophagitis
IV injection dosage for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux oesophagitis, and Zollinger-Ellison syndrome
Specific dosage recommendations for different patient groups based on body weight

Administered orally and intravenously
Specific directions for use of IV Injection and IV Infusion, including reconstitution, administration duration, and solution preparation

Potential interactions with ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole, amoxycillin, phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, antacids, piroxicam, diclofenac, naproxen, alcohol, food, and digoxin

Contraindicated in patients with known hypersensitivity to Omeprazole
Possibility of malignancy should be excluded before treatment, if gastric ulcer is suspected

Common side effects include skin rash, urticaria, pruritus, photosensitivity, diarrhea, headache, constipation, nausea/vomiting, abdominal pain, dry mouth, stomatitis, candidiasis, paraesthesia, dizziness, light headedness, feeling faint, somnolence, insomnia, vertigo, reversible mental confusion, agitation, depression, hallucinations, arthritic and myalgic symptoms, blurred vision, taste disturbance, peripheral edema, increased sweating, gynaecomastia, leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock, malaise, fever, bronchospasm, encephalopathy, hepatitis with or without jaundice, interstitial nephritis, hepatic failure, and increases in liver enzymes

Results from three epidemiological studies indicate no adverse effects on pregnancy or the health of the fetus/newborn child
Omeprazole can be used during pregnancy
Caution is advised during lactation, and breast-feeding should be discontinued if essential

Avoid concomitant use of clopidogrel with SB-Omec
Observational studies suggest a potential increased risk for osteoporosis-related fractures with PPI therapy
Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term SB-Omec users
Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities