Ometem 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Omeprazole
Company Team pharmaceuticals ltd
Also available as
Ometem 40 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Eradication regimen in peptic ulcer disease

Pharmacology

  • Substituted benzimidazole
  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral administration
  • Benign gastric and duodenal ulcer dosage of 20 mg once daily for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration

Administration

  • IV Injection
  • IV Infusion
  • Intravenous administration only
  • Slow intravenous injection
  • Intravenous infusion over a period of 20-30 minutes or more

Interaction

  • Decreased intragastric acidity may reduce absorption of ketoconazole
  • Metabolized in the liver through cytochrome P450
  • Can delay the elimination of diazepam, phenytoin, and warfarin

Contraindications

  • Known hypersensitivity

Side Effects

  • Skin rash
  • Urticaria
  • Pruritus
  • Photosensitivity
  • Diarrhea
  • Headache
  • Constipation
  • Nausea/vomiting
  • Paraesthesia
  • Dizziness
  • Mental confusion
  • Agranulocytosis
  • Pancytopenia
  • Increased liver enzymes

Pregnancy & Lactation

  • Safe for use in pregnancy
  • No adverse effects on pregnancy or fetus

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term treatment
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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